3fr1

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[[Image:3fr1.png|left|200px]]
 
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{{STRUCTURE_3fr1| PDB=3fr1 | SCENE= }}
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==NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)==
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<StructureSection load='3fr1' size='340' side='right'caption='[[3fr1]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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===NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3fr1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FR1 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_19684598}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fr1 OCA], [https://pdbe.org/3fr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fr1 RCSB], [https://www.ebi.ac.uk/pdbsum/3fr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fr1 ProSAT]</span></td></tr>
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[[3fr1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FR1 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
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<ref group="xtra">PMID:019684598</ref><references group="xtra"/>
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__TOC__
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[[Category: Eisenberg, D.]]
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</StructureSection>
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[[Category: Sawaya, M R.]]
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[[Category: Homo sapiens]]
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[[Category: Wiltzius, J J.W.]]
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[[Category: Large Structures]]
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[[Category: Amidation]]
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[[Category: Eisenberg D]]
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[[Category: Amyloid]]
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[[Category: Sawaya MR]]
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[[Category: Amyloid-like protofibril]]
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[[Category: Wiltzius JJW]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Hormone]]
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[[Category: Protein fibril]]
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[[Category: Secreted]]
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Current revision

NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)

PDB ID 3fr1

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OCA

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