4i0h

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'''Unreleased structure'''
 
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The entry 4i0h is ON HOLD until Paper Publication
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==SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors.==
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<StructureSection load='4i0h' size='340' side='right'caption='[[4i0h]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4i0h]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I0H FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1BL:(2R)-5-{[(2S,3R)-4-{[1-(3-TERT-BUTYLPHENYL)CYCLOHEXYL]AMINO}-1-(3,5-DIFLUOROPHENYL)-3-HYDROXYBUTAN-2-YL]AMINO}-2-HYDROXY-5-OXOPENTANOIC+ACID'>1BL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i0h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0h OCA], [https://pdbe.org/4i0h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i0h RCSB], [https://www.ebi.ac.uk/pdbsum/4i0h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i0h ProSAT]</span></td></tr>
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</table>
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Authors: Yao, N., Brecht, E.
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==See Also==
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*[[Beta secretase 3D structures|Beta secretase 3D structures]]
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Description: SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors.
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Brecht E]]
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[[Category: Yao N]]

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SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors.

PDB ID 4i0h

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