3goq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3goq" [edit=sysop:move=sysop])
Current revision (07:09, 6 September 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3goq.png|left|200px]]
 
-
{{STRUCTURE_3goq| PDB=3goq | SCENE= }}
+
==Crystal structure of the Tyr13Met variant of Bacillus subtilis ferrochelatase==
-
 
+
<StructureSection load='3goq' size='340' side='right'caption='[[3goq]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
===Crystal structure of the Tyr13Met variant of Bacillus subtilis ferrochelatase===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3goq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GOQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GOQ FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
==About this Structure==
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
[[3goq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GOQ OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3goq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3goq OCA], [https://pdbe.org/3goq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3goq RCSB], [https://www.ebi.ac.uk/pdbsum/3goq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3goq ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CPFC_BACSU CPFC_BACSU] Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:25646457, PubMed:25908396). Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III (PubMed:25646457, PubMed:25908396). It can also insert iron into protoporphyrin IX (PubMed:1459957, PubMed:8119288, PubMed:21052751, PubMed:25646457). Has weaker activity with 2,4 disulfonate, deuteroporphyrin and 2,4 hydroxyethyl (PubMed:25646457, PubMed:12761666). In vitro, can also use Zn(2+) or Cu(2+) (PubMed:8119288, PubMed:16140324, PubMed:21052751, PubMed:12761666).<ref>PMID:12761666</ref> <ref>PMID:1459957</ref> <ref>PMID:16140324</ref> <ref>PMID:21052751</ref> <ref>PMID:25646457</ref> <ref>PMID:25826316</ref> <ref>PMID:25908396</ref> <ref>PMID:8119288</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/go/3goq_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3goq ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Ferrochelatase|Ferrochelatase]]
+
*[[Ferrochelatase 3D structures|Ferrochelatase 3D structures]]
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
-
[[Category: Ferrochelatase]]
+
[[Category: Large Structures]]
-
[[Category: Al-Karadaghi, S.]]
+
[[Category: Al-Karadaghi S]]
-
[[Category: Hansson, M.]]
+
[[Category: Hansson M]]
-
[[Category: Hansson, M D.]]
+
[[Category: Hansson MD]]
-
[[Category: Karlberg, T]]
+
[[Category: Karlberg T]]
-
[[Category: Heme biosynthesis]]
+
-
[[Category: Iron]]
+
-
[[Category: Lyase]]
+
-
[[Category: Metal-binding]]
+
-
[[Category: Porphyrin biosynthesis]]
+

Current revision

Crystal structure of the Tyr13Met variant of Bacillus subtilis ferrochelatase

PDB ID 3goq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3goq"
Personal tools