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3giu
From Proteopedia
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| - | [[Image:3giu.png|left|200px]] | ||
| - | + | ==1.25 Angstrom Crystal Structure of Pyrrolidone-Carboxylate Peptidase (pcp) from Staphylococcus aureus== | |
| - | + | <StructureSection load='3giu' size='340' side='right'caption='[[3giu]], [[Resolution|resolution]] 1.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3giu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staac Staac]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GIU FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | == | + | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [[3giu]] is a 2 chain structure with sequence from [ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pcp, SACOL2714 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=93062 STAAC])</td></tr> |
| + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pyroglutamyl-peptidase_I Pyroglutamyl-peptidase I], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.19.3 3.4.19.3] </span></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3giu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3giu OCA], [https://pdbe.org/3giu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3giu RCSB], [https://www.ebi.ac.uk/pdbsum/3giu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3giu ProSAT], [https://www.topsan.org/Proteins/CSGID/3giu TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/PCP_STAAC PCP_STAAC]] Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gi/3giu_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3giu ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Pyroglutamyl-peptidase I]] | [[Category: Pyroglutamyl-peptidase I]] | ||
| - | [[Category: | + | [[Category: Staac]] |
| - | [[Category: Anderson, W F | + | [[Category: Anderson, W F]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: Minasov, G | + | [[Category: Minasov, G]] |
| - | [[Category: Onopriyenko, O | + | [[Category: Onopriyenko, O]] |
| - | [[Category: Peterson, S N | + | [[Category: Peterson, S N]] |
| - | [[Category: Savchenko, A | + | [[Category: Savchenko, A]] |
| - | [[Category: Skarina, T | + | [[Category: Skarina, T]] |
| - | [[Category: Wawrzak, Z | + | [[Category: Wawrzak, Z]] |
| - | + | ||
[[Category: Csgid]] | [[Category: Csgid]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
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[[Category: Protease]] | [[Category: Protease]] | ||
[[Category: Pyrrolidone-carboxylate peptidase]] | [[Category: Pyrrolidone-carboxylate peptidase]] | ||
| - | [[Category: Structural genomic]] | ||
[[Category: Thiol protease]] | [[Category: Thiol protease]] | ||
Current revision
1.25 Angstrom Crystal Structure of Pyrrolidone-Carboxylate Peptidase (pcp) from Staphylococcus aureus
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