3gqv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3gqv" [edit=sysop:move=sysop])
Current revision (07:10, 6 September 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3gqv.png|left|200px]]
 
-
{{STRUCTURE_3gqv| PDB=3gqv | SCENE= }}
+
==Lovastatin polyketide enoyl reductase (LovC) mutant K54S with bound NADP==
-
 
+
<StructureSection load='3gqv' size='340' side='right'caption='[[3gqv]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
-
===Lovastatin polyketide enoyl reductase (LovC) mutant K54S with bound NADP===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3gqv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_terreus Aspergillus terreus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GQV FirstGlance]. <br>
-
 
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
-
==About this Structure==
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-
[[3gqv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_terreus Aspergillus terreus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GQV OCA].
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gqv OCA], [https://pdbe.org/3gqv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gqv RCSB], [https://www.ebi.ac.uk/pdbsum/3gqv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gqv ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/LOVC_ASPTE LOVC_ASPTE] Catalyzes the NADPH-dependent reduction of the unsaturated tetra-, penta- and heptaketide intermediates that arise during the LovB-mediated biosynthesis of the lovastatin nonaketide chain.<ref>PMID:10334994</ref> <ref>PMID:19900898</ref> <ref>PMID:22733743</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/3gqv_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gqv ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Aspergillus terreus]]
[[Category: Aspergillus terreus]]
-
[[Category: Ames, B D.]]
+
[[Category: Large Structures]]
-
[[Category: Kaake, R.]]
+
[[Category: Ames BD]]
-
[[Category: Li, J W.]]
+
[[Category: Kaake R]]
-
[[Category: Ma, S M.]]
+
[[Category: Li JW]]
-
[[Category: Smith, P T.]]
+
[[Category: Ma SM]]
-
[[Category: Tang, Y.]]
+
[[Category: Smith PT]]
-
[[Category: Tsai, S C.]]
+
[[Category: Tang Y]]
-
[[Category: Vederas, J C.]]
+
[[Category: Tsai S-C]]
-
[[Category: Wong, E W.]]
+
[[Category: Vederas JC]]
-
[[Category: Wong, S K.]]
+
[[Category: Wong EW]]
-
[[Category: Xie, X.]]
+
[[Category: Wong SK]]
-
[[Category: Nadp-binding]]
+
[[Category: Xie X]]
-
[[Category: Oxidoreductase]]
+
-
[[Category: Rossmann fold]]
+

Current revision

Lovastatin polyketide enoyl reductase (LovC) mutant K54S with bound NADP

PDB ID 3gqv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3gqv"
Personal tools