2aq2

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[[Image:2aq2.gif|left|200px]]<br /><applet load="2aq2" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2aq2, resolution 1.800&Aring;" />
 
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'''Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant'''<br />
 
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==About this Structure==
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==Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant==
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2AQ2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=SO4:'>SO4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA].
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<StructureSection load='2aq2' size='340' side='right'caption='[[2aq2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2aq2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AQ2 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aq2 OCA], [https://pdbe.org/2aq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aq2 RCSB], [https://www.ebi.ac.uk/pdbsum/2aq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aq2 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TVB5_MOUSE TVB5_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aq/2aq2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aq2 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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The nitty-gritty of protein interactions., Schreiber G, Structure. 2005 Dec;13(12):1737-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16338399 16338399]
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*[[T-cell receptor 3D structures|T-cell receptor 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
 
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Cho, S.]]
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[[Category: Cho S]]
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[[Category: Guan, R.]]
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[[Category: Guan R]]
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[[Category: Kerzic, M C.]]
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[[Category: Kerzic MC]]
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[[Category: Kieke, M C.]]
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[[Category: Kieke MC]]
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[[Category: Kranz, D M.]]
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[[Category: Kranz DM]]
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[[Category: Mariuzza, R A.]]
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[[Category: Mariuzza RA]]
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[[Category: Sundberg, E J.]]
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[[Category: Sundberg EJ]]
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[[Category: Swaminathan, C P.]]
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[[Category: Swaminathan CP]]
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[[Category: Yang, J.]]
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[[Category: Yang J]]
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[[Category: NA]]
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[[Category: SO4]]
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[[Category: ZN]]
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[[Category: complex structure]]
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[[Category: staphlococcal enterotoxin c3]]
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[[Category: t-cell receptor v beta domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:29:47 2008''
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Current revision

Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant

PDB ID 2aq2

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