Ribosomal protein L8

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[[Image:RPL8.png|left|200px|thumb|Crystal Structure of Ribosomal protein L8 from ''Thermomyces lanuginosus'' ([[3jyw]], chain G)]]
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<StructureSection load='4v7h' size='350' side='right' scene='43/433124/Cv/1' caption='Ribosomal protein L8 (PDB code [[4v7h]])'>
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{{STRUCTURE_3jyw| PDB=3jyw | SIZE=400| SCENE=Ribosomal_protein_L8/Cv/1 |right|CAPTION=Ribosomal protein L8 from ''Thermomyces lanuginosus'' [[3jyw]], chain G }}
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[[Ribosomal protein L8]] (RPL8) is one of the 34 proteins which belong to the large 50S subunit of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is known to bind to the 5S RRNA from the large subunit. It is located in the aminoacyl-tRNA binding site of the peptidyltransferase center<ref>PMID:22893726</ref>. In the archaea like in ''Haloarcula marismortui'' the L8 is called L8P (RPL8P).
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</StructureSection>
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== References ==
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[[Ribosomal protein L8]] (RPL8) is one of the 34 proteins which belong to the large 50S subunit of the prokaryotic ribosome or to the ca. 49 proteins in the large 60S subunit of the eukaryotic ribosome. It is known to bind to the 5S RRNA from the large subunit. It is located in the aminoacyl-tRNA binding site of the peptidyltransferase center. In the archaea like in Haloarcula marismortui the L8 is called L8P (RPL8P). The images at the left and at the right correspond to one representative RPL8, i.e. the crystal structure of Ribosomal protein L8 from ''Thermomyces lanuginosus'' ([[3jyw]], chain G).
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== 3D Structures of Ribosomal protein L8 ==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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===L8 in 60S subunit===
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[[3jyw]] - RPL8 in 60S subunit – ''Thermomyces lanuginosus'' – Cryo-EM<br />
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[[1s1i]] - yRPL8 in 40S ribosomal subunit+18S RRNA+elongation factor 2 – Cryo-EM – yeast<br />
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[[3o58]], [[3o5h]] - yRPL8 in 60S ribosomal subunit+25S RRNA+5S RRNA+5.8S RRNA<br />
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[[3izs]] – yRPL8 in 60S ribosomal subunit – Cryo-EM<br />
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[[3j0t]], [[3j0w]], [[3j0y]], [[3j11]], [[3j12]], [[3j14]] – EcRPL8 in 50S subunit+5S RRNA+23S RRNA – ''Escherichia coli'' - Cryo-EM<br />
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[[3uos]] – EcRPL8 in 50S subunit+5S RRNA+23S RRNA<br />
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[[3u5e]], [[3u5i]] – yRPL8 in 60S ribosomal subunit<br />
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[[4a17]], [[4a1a]], [[4a1c]], [[4a1e]] - RPL8 in 60S ribosomal subunit + 5S RRNA + 5.8S RRNA – ''Tetrahymna thermophila''<br />
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[[4b6a]] - yRPL7 in 60S ribosomal subunit + P0 + P1 +P2 + ARX1 - Cryo-EM
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===L8 in large + small ribosomal subunit===
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[[2zkr]] - RPL8 in 60S ribosomal subunit+30S ribosomal subunit+28S RRNA+5.8S RRNA – Cryo-EM – dog
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[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Ribosomal protein L8 (PDB code 4v7h)

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References

  1. Jakovljevic J, Ohmayer U, Gamalinda M, Talkish J, Alexander L, Linnemann J, Milkereit P, Woolford JL Jr. Ribosomal proteins L7 and L8 function in concert with six A(3) assembly factors to propagate assembly of domains I and II of 25S rRNA in yeast 60S ribosomal subunits. RNA. 2012 Oct;18(10):1805-22. doi: 10.1261/rna.032540.112. Epub 2012 Aug 14. PMID:22893726 doi:http://dx.doi.org/10.1261/rna.032540.112

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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