4hq0

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'''Unreleased structure'''
 
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The entry 4hq0 is ON HOLD until Paper Publication
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==Crystal Structure of mutant form of Caspase-7==
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<StructureSection load='4hq0' size='340' side='right'caption='[[4hq0]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4hq0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HQ0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hq0 OCA], [https://pdbe.org/4hq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hq0 RCSB], [https://www.ebi.ac.uk/pdbsum/4hq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hq0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
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Authors: Lee, Y., Kang, H.J., Bae, K.-H., Kim, S.J., Chung, S.J.
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==See Also==
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*[[Caspase 3D structures|Caspase 3D structures]]
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Description: Crystal Structure of mutant form of Caspase-7
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Bae K-H]]
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[[Category: Chung SJ]]
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[[Category: Kang HJ]]
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[[Category: Kim SJ]]
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[[Category: Lee Y]]

Current revision

Crystal Structure of mutant form of Caspase-7

PDB ID 4hq0

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