This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4jd6
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4jd6 is ON HOLD Authors: Biswas, T., Chen, W., Garneau-Tsodikova, S., Tsodikov, O.V. Description: Crystal structure of Acto complex) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Mycobacterium tuberculosis Eis in complex with coenzyme A and tobramycin== | |
| - | + | <StructureSection load='4jd6' size='340' side='right'caption='[[4jd6]], [[Resolution|resolution]] 3.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4jd6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JD6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JD6 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=TOY:TOBRAMYCIN'>TOY</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jd6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jd6 OCA], [https://pdbe.org/4jd6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jd6 RCSB], [https://www.ebi.ac.uk/pdbsum/4jd6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jd6 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/EIS_MYCTU EIS_MYCTU] May participate in pathogenesis, possibly by enhancing survival of the bacteria in host macrophages during infection.<ref>PMID:10629183</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
| + | [[Category: Biswas T]] | ||
| + | [[Category: Chen W]] | ||
| + | [[Category: Garneau-Tsodikova S]] | ||
| + | [[Category: Tsodikov OV]] | ||
Current revision
Crystal structure of Mycobacterium tuberculosis Eis in complex with coenzyme A and tobramycin
| |||||||||||
