3vpm

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[[Image:3vpm.jpg|left|200px]]
 
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{{STRUCTURE_3vpm| PDB=3vpm | SCENE= }}
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==Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant==
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<StructureSection load='3vpm' size='340' side='right'caption='[[3vpm]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3vpm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VPM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vpm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vpm OCA], [https://pdbe.org/3vpm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vpm RCSB], [https://www.ebi.ac.uk/pdbsum/3vpm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vpm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RIR2_HUMAN RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
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===Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant===
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==See Also==
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*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3vpm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPM OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Large Structures]]
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[[Category: Chen, B.]]
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[[Category: Chen B]]
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[[Category: Chen, X.]]
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[[Category: Chen X]]
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[[Category: Liu, H.]]
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[[Category: Liu H]]
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[[Category: Shao, J.]]
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[[Category: Shao J]]
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[[Category: Xu, Z.]]
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[[Category: Xu Z]]
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[[Category: Yang, C.]]
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[[Category: Yang C]]
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[[Category: Zhang, L.]]
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[[Category: Zhang L]]
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[[Category: Zhu, L.]]
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[[Category: Zhu L]]
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[[Category: Zhu, W.]]
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[[Category: Zhu W]]
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[[Category: Metal-binding]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal structure of human ribonucleotide reductase subunit M2 (hRRM2) mutant

PDB ID 3vpm

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OCA

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