4i0j

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[[Image:4i0j.jpg|left|200px]]
 
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{{STRUCTURE_4i0j| PDB=4i0j | SCENE= }}
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==SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors==
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<StructureSection load='4i0j' size='340' side='right'caption='[[4i0j]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4i0j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4I0J FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=842:N-[(1S,2R)-1-(3,5-DIFLUOROBENZYL)-2-HYDROXY-3-({1-[3-(1H-PYRAZOL-1-YL)PHENYL]CYCLOHEXYL}AMINO)PROPYL]ACETAMIDE'>842</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4i0j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4i0j OCA], [https://pdbe.org/4i0j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4i0j RCSB], [https://www.ebi.ac.uk/pdbsum/4i0j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4i0j ProSAT]</span></td></tr>
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</table>
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===SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors===
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==See Also==
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*[[Beta secretase 3D structures|Beta secretase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4i0j]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4I0J OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Memapsin 2]]
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[[Category: Large Structures]]
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[[Category: Brecht, E.]]
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[[Category: Brecht E]]
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[[Category: Yao, N.]]
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[[Category: Yao N]]
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[[Category: Bace asp protease]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Hydrolysis]]
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Current revision

SPR and structural analysis yield insight towards mechanism of inhibition of BACE inhibitors

PDB ID 4i0j

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