3hit
From Proteopedia
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| - | [[Image:3hit.png|left|200px]] | ||
| - | + | ==Crystal structure of Saporin-L1 in complex with the dinucleotide inhibitor, a transition state analogue== | |
| - | + | <StructureSection load='3hit' size='340' side='right'caption='[[3hit]], [[Resolution|resolution]] 2.29Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3hit]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HIT FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DYN:5-O-[(S)-{[(3R,4R)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-({[(S)-hydroxy(3-hydroxypropoxy)phosphoryl]oxy}methyl)pyrrolidin-3-yl]oxy}(hydroxy)phosphoryl]-3-O-[(R)-hydroxy(4-hydroxybutoxy)phosphoryl]-2-O-methylguanosine'>DYN</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hit OCA], [https://pdbe.org/3hit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hit RCSB], [https://www.ebi.ac.uk/pdbsum/3hit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hit ProSAT]</span></td></tr> |
| - | [[3hit]] is a 2 chain structure with sequence from [ | + | </table> |
| - | + | == Function == | |
| - | == | + | [https://www.uniprot.org/uniprot/Q2QEH4_SAPOF Q2QEH4_SAPOF] |
| - | < | + | == Evolutionary Conservation == |
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/3hit_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hit ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Saponaria officinalis]] | [[Category: Saponaria officinalis]] | ||
| - | + | [[Category: Almo SC]] | |
| - | [[Category: Almo | + | [[Category: Ho M]] |
| - | [[Category: Ho | + | [[Category: Schramm VL]] |
| - | [[Category: Schramm | + | [[Category: Sturm MB]] |
| - | [[Category: Sturm | + | |
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Current revision
Crystal structure of Saporin-L1 in complex with the dinucleotide inhibitor, a transition state analogue
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