2b0o
From Proteopedia
(Difference between revisions)
| (12 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2b0o.gif|left|200px]]<br /><applet load="2b0o" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2b0o, resolution 2.06Å" /> | ||
| - | '''Crystal structure of UPLC1 GAP domain'''<br /> | ||
| - | == | + | ==Crystal structure of UPLC1 GAP domain== |
| - | + | <StructureSection load='2b0o' size='340' side='right'caption='[[2b0o]], [[Resolution|resolution]] 2.06Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2b0o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B0O FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.06Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b0o OCA], [https://pdbe.org/2b0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b0o RCSB], [https://www.ebi.ac.uk/pdbsum/2b0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b0o ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ASAP3_HUMAN ASAP3_HUMAN] Promotes cell proliferation.<ref>PMID:14654939</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b0/2b0o_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b0o ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith C]] |
| - | [[Category: Bochkarev | + | [[Category: Bochkarev A]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Ismail | + | [[Category: Ismail S]] |
| - | [[Category: Park | + | [[Category: Park H]] |
| - | + | [[Category: Shen L]] | |
| - | [[Category: Shen | + | [[Category: Sundstrom M]] |
| - | [[Category: Sundstrom | + | [[Category: Weigelt J]] |
| - | [[Category: Weigelt | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of UPLC1 GAP domain
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith C | Bochkarev A | Edwards A | Ismail S | Park H | Shen L | Sundstrom M | Weigelt J
