Cytochrome c peroxidase

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:27, 9 January 2020) (edit) (undo)
 
(22 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_1dcc| PDB=1dcc | SIZE=400| SCENE= |right|CAPTION=Yeast cytochrome c peroxidase complex with O2, [[1dcc]] }}
+
<StructureSection load='' size='350' side='right' caption='Yeast heme-containing cytochrome c peroxidase complex with O2 (PDB entry [[1dcc]])' scene='46/466465/Cv/1'>
-
'''Cytochrome c peroxidase''' (CcP) is a protoporphyrin-containing enzyme which reduces hydrogen peroxide to water.
+
'''Cytochrome c peroxidase''' (CcP) is a protoporphyrin-containing enzyme which reduces hydrogen peroxide to water.<ref>PMID:17027371</ref>
-
{{TOC limit|limit=2}}
+
See also [[Hemeproteins]].
-
== 3D Structures of cytochrome c peroxidase ==
+
== Structural highlights ==
-
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+
The <scene name='46/466465/Cv/3'>O2 molecule in the active site coordinates with the heme</scene> (PDB entry [[1dcc]]).<ref>PMID:7664080</ref> Water molecules are shown as red spheres.
-
 
+
-
[[2cyp]], [[1ccp]], [[1cca]], [[1ccb]], [[1ccc]], [[1cmq]], [[1cce]], [[1ccg]], [[2cep]], [[1cmt]], [[1cmu]], [[3ccx]], [[4ccx]], [[1bek]], [[1bem]], [[1bep]], [[1beq]], [[1bes]], [[1kok]], [[1zby]], [[1zbz]], [[1s73]], [[1sbm]], [[1z53]], [[2ia8]], [[2xil]], [[2xj5]], [[2xj8]], [[2ycg]], [[3r98]], [[3r99]] – yCcP – yeast<br />
+
-
[[2ccp]], [[3ccp]], [[4ccp]], [[5ccp]], [[6ccp]], [[7ccp]], [[1cyf]], [[1ryc]], [[1cci]], [[1aa4]], [[1ccj]], [[1bej]], [[1a2f]], [[1a2g]], [[1cck]], [[1ccl]], [[1bj9]], [[1dj1]], [[1jci]], [[1kxm]], [[1kxn]], [[1mk8]], [[1mkq]], [[1mkr]], [[1sog]], [[1stq]], [[2v23]], [[3e2n]], [[3e2o]], [[3m23]], [[3m25]], [[3m26]], [[3m27]], [[3m28]], [[3m29]], [[3m2a]], [[3m2b]], [[3m2c]], [[3m2d]], [[3m2e]], [[3m2f]], [[3m2g]], [[3m2h]], [[3m2i]], [[2x07]], [[2x08]], [[4a7m]] – yCcP (mutant) <br />
+
-
[[1ml2]] - yCcP (mutant) with Zn-oxo-protoporphyrin<br />
+
-
[[1ebe]] – yCcP – Laue<br />
+
-
[[4dy9]] - CcP - ''Leishmania major''
+
-
 
+
-
===CcP containing di-haem===
+
-
 
+
-
[[1eb7]], [[2vhd]] – CcP – ''Pseudomonas aeruginosa''<br />
+
-
[[1nml]], [[1rz5]], [[1rz6]] – CcP – ''Marinobacter hydrocarbonoclasticus''<br />
+
-
[[1zzh]] – CcP – ''Rhodobacter capsulatus''<br />
+
-
[[1c1u]], [[1c1v]], [[2c1u]], [[2c1v]] – CcP – ''Paracoccus pantotrophus''
+
-
 
+
-
===CcP complex with cytochrome C===
+
-
 
+
-
[[2pcb]], [[1u75]] – yCcP + cytochrome C<br />
+
-
[[2pcc]] - yCcP + iso-1-cytochrome C<br />
+
-
[[2gb8]] - yCcP + iso-1-cytochrome C - NMR<br />
+
-
[[1s6v]], [[2b11]], [[2jti]] - yCcP (mutant) + iso-1-cytochrome C (mutant) <br />
+
-
[[1u74]], [[2b0z]], [[2b10]], [[2b12]], [[2bcn]] - yCcP + iso-1-cytochrome C (mutant)
+
-
 
+
-
===CcP complex with small molecule===
+
-
 
+
-
[[1cmp]] – yCcP + dimethylazolium<br />
+
-
[[1dcc]] – yCcP + O2<br />
+
-
[[1sdq]] – yCcP + NO<br />
+
-
[[1cpd]], [[1cpe]], [[1cpg]] – yCcP + cation<br />
+
-
[[1jdr]], [[1krj]] - yCcP (mutant) + cation<br />
+
-
[[1cpf]] – yCcP + Tris<br />
+
-
[[1ac4]], [[1ac8]], [[1aeb]], [[1aed]], [[1aeh]], [[1aej]], [[1aen]], [[1aev]] – yCcP (mutant) + thiazole derivative<br />
+
-
[[1aee]] - yCcP (mutant) + aniline<br />
+
-
[[1aek]] - yCcP (mutant) + indoline<br />
+
-
[[1aef]], [[1aeg]], [[1aem]], [[1aeo]], [[2anz]], [[2aqd]], [[2eun]], [[2euo]], [[2eur]], [[2rbw]], [[2rbz]], [[2rc2]], [[2y5a]] - yCcP (mutant) + pyridine derivative<br />
+
-
[[2rbx]] - yCcP (mutant) + pyrimidine derivative<br />
+
-
[[1aeq]], [[1aes]], [[1aet]], [[1aeu]], [[1ds4]], [[1dse]], [[1dsg]], [[1dsp]], [[2euu]], [[2rby]], [[1dso]] - yCcP (mutant) + imidazole derivative<br />
+
-
[[2as1]] - yCcP (mutant) + thiopheneneamidine<br />
+
-
[[2rbu]] - yCcP (mutant) + carboximidamide<br />
+
-
[[2as2]], [[2rc0]] - yCcP (mutant) + piperidine derivative<br />
+
-
[[2as3]], [[4a6z]], [[4a71]], [[4a78]]- yCcP (mutant) + phenol derivative<br />
+
-
[[2rc1]] - yCcP (mutant) + oxazoline<br />
+
-
[[2as4]] - yCcP (mutant) + flurocatechol<br />
+
-
[[2as6]], [[2euq]], [[2eus]], [[2rbv]], [[2rbt]] - yCcP (mutant) + amine derivative<br />
+
-
[[2eup]], [[2eut]] - yCcP (mutant) + picoline derivative<br />
+
-
[[2v2e]] - yCcP (mutant) + isoniazid<br />
+
-
[[1bva]] - yCcP (mutant) + Mn<br />
+
-
[[2icv]] – yCcP + Co<br />
+
-
[[1dj5]] - yCcP (mutant) + hydroxyguanidine<br />
+
-
[[3exb]] - yCcP (mutant) + peptide
+
-
 
+
-
===Cytochrome c551 peroxidase===
+
-
 
+
-
[[3hq6]], [[4aal]], [[4aam]], [[4aan]] – GsCc551P – ''Geobacter sulfurreducens''<br />
+
-
[[3hq7]], [[3hq8]], [[3hq9]], [[4aao]] – GsCc551P (mutant)<br />
+
-
[[3o5c]] – Cc551P – ''Shewanella oneidensis''
+
 +
== 3D Structures of cytochrome c peroxidase ==
 +
[[Cytochrome c peroxidase 3D structures]]
 +
</StructureSection>
 +
== References ==
 +
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Yeast heme-containing cytochrome c peroxidase complex with O2 (PDB entry 1dcc)

Drag the structure with the mouse to rotate

References

  1. ↑ Atack JM, Kelly DJ. Structure, mechanism and physiological roles of bacterial cytochrome c peroxidases. Adv Microb Physiol. 2007;52:73-106. PMID:17027371 doi:http://dx.doi.org/10.1016/S0065-2911(06)52002-8
  2. ↑ Miller MA, Shaw A, Kraut J. 2.2 A structure of oxy-peroxidase as a model for the transient enzyme: peroxide complex. Nat Struct Biol. 1994 Aug;1(8):524-31. PMID:7664080

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

Retrieved from "http://52.214.119.220/wiki/index.php/Cytochrome_c_peroxidase"
Personal tools