2l5x
From Proteopedia
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| - | {{Large structure}} | ||
| - | {{STRUCTURE_2l5x| PDB=2l5x | SCENE= }} | ||
| - | ===Solution structure of IL1A-S100A13 complex=== | ||
| - | {{ABSTRACT_PUBMED_021270123}} | ||
| - | == | + | ==Solution structure of IL1A-S100A13 complex== |
| - | [[2l5x]] is a 4 chain structure with sequence from [ | + | <StructureSection load='2l5x' size='340' side='right'caption='[[2l5x]]' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2l5x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L5X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L5X FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l5x OCA], [https://pdbe.org/2l5x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l5x RCSB], [https://www.ebi.ac.uk/pdbsum/2l5x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l5x ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IL1A_HUMAN IL1A_HUMAN] Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. | ||
==See Also== | ==See Also== | ||
| - | *[[Interleukin|Interleukin]] | + | *[[Interleukin 3D structures|Interleukin 3D structures]] |
| + | *[[S100 proteins 3D structures|S100 proteins 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mohan SK]] |
| - | [[Category: | + | [[Category: Yu C]] |
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Current revision
Solution structure of IL1A-S100A13 complex
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