3i55

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{{Large structure}}
 
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{{STRUCTURE_3i55| PDB=3i55 | SCENE= }}
 
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===Co-crystal structure of Mycalamide A Bound to the Large Ribosomal Subunit===
 
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{{ABSTRACT_PUBMED_19738021}}
 
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==About this Structure==
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==Co-crystal structure of Mycalamide A Bound to the Large Ribosomal Subunit==
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[[3i55]] is a 31 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui] and [http://en.wikipedia.org/wiki/Haloarcula_marismortui_atcc_43049 Haloarcula marismortui atcc 43049]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I55 OCA].
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<StructureSection load='3i55' size='340' side='right'caption='[[3i55]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
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== Structural highlights ==
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==See Also==
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<table><tr><td colspan='2'>[[3i55]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui] and [https://en.wikipedia.org/wiki/Haloarcula_marismortui_ATCC_43049 Haloarcula marismortui ATCC 43049]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I55 FirstGlance]. <br>
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*[[Ribosomal protein L10|Ribosomal protein L10]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11&#8491;</td></tr>
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*[[Ribosomal protein L11|Ribosomal protein L11]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=2OP:(2S)-2-HYDROXYPROPANOIC+ACID'>2OP</scene>, <scene name='pdbligand=5AA:N6-DIMETHYL-3-AMINO-ADENOSINE-5-MONOPHOSPHATE'>5AA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYL:MYCALAMIDE+A'>MYL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PO2:HYPOPHOSPHITE'>PO2</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene></td></tr>
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*[[Ribosomal protein L13|Ribosomal protein L13]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i55 OCA], [https://pdbe.org/3i55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i55 RCSB], [https://www.ebi.ac.uk/pdbsum/3i55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i55 ProSAT]</span></td></tr>
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*[[Ribosomal protein L14|Ribosomal protein L14]]
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</table>
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*[[Ribosomal protein L19|Ribosomal protein L19]]
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== Function ==
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*[[Ribosomal protein L2|Ribosomal protein L2]]
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[https://www.uniprot.org/uniprot/RL2_HALMA RL2_HALMA] One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).[HAMAP-Rule:MF_01320_A]
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*[[Ribosomal protein L21|Ribosomal protein L21]]
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== Evolutionary Conservation ==
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*[[Ribosomal protein L3|Ribosomal protein L3]]
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[[Image:Consurf_key_small.gif|200px|right]]
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*[[Ribosomal protein L34|Ribosomal protein L34]]
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Check<jmol>
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*[[Ribosomal protein L4|Ribosomal protein L4]]
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<jmolCheckbox>
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*[[Ribosomal protein L5|Ribosomal protein L5]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i5/3i55_consurf.spt"</scriptWhenChecked>
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*[[Ribosomal protein L6|Ribosomal protein L6]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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*[[Ribosomal protein L7|Ribosomal protein L7]]
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i55 ConSurf].
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<ref group="xtra">PMID:019738021</ref><references group="xtra"/>
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
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[[Category: Haloarcula marismortui atcc 43049]]
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[[Category: Haloarcula marismortui ATCC 43049]]
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[[Category: Blaha, G.]]
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[[Category: Large Structures]]
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[[Category: Gurel, G.]]
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[[Category: Blaha G]]
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[[Category: Moore, P B.]]
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[[Category: Gurel G]]
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[[Category: Steitz, T A.]]
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[[Category: Moore PB]]
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[[Category: Large ribosomal subunit]]
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[[Category: Steitz TA]]
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[[Category: Metal-binding]]
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[[Category: Mycalamide some]]
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[[Category: Ribonucleoprotein]]
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[[Category: Ribosomal protein]]
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[[Category: Ribosome-antibiotic complex]]
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[[Category: Rna-binding]]
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[[Category: Rrna-binding]]
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[[Category: Trna-binding]]
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[[Category: Zinc-finger]]
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Current revision

Co-crystal structure of Mycalamide A Bound to the Large Ribosomal Subunit

PDB ID 3i55

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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