3ow2
From Proteopedia
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| - | {{Large structure}} | ||
| - | {{STRUCTURE_3ow2| PDB=3ow2 | SCENE= }} | ||
| - | ===Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit=== | ||
| - | == | + | ==Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit== |
| - | [[3ow2]] is a | + | <StructureSection load='3ow2' size='340' side='right'caption='[[3ow2]], [[Resolution|resolution]] 2.70Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ow2]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OW2 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EMK:(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ETHYL-3,4,10-TRIHYDROXY-3,5,6,8,10,12,14-HEPTAMETHYL-15-OXO-11-[(3,4,6-TRIDEOXY-3-{[3-(1-{(1S,2R)-1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL}-1H-1,2,3-TRIAZOL-4-YL)PROPYL](METHYL)AMINO}-BETA-D-XYLO-HEXOPYRANOSYL)OXY]-1-OXA-6-AZACYCLOPENTADECAN-13-YL+2,6-DIDEOXY-3-C-METHYL-3-O-METHYL-ALPHA-L-RIBO-HEXOPYRANOSIDE'>EMK</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SR:STRONTIUM+ION'>SR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ow2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ow2 OCA], [https://pdbe.org/3ow2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ow2 RCSB], [https://www.ebi.ac.uk/pdbsum/3ow2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ow2 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RL2_HALMA RL2_HALMA] One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).[HAMAP-Rule:MF_01320_A] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Haloarcula marismortui]] | [[Category: Haloarcula marismortui]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Kanyo ZF]] |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit
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