1s72

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{{Large structure}}
 
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{{STRUCTURE_1s72| PDB=1s72 | SCENE= }}
 
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===REFINED CRYSTAL STRUCTURE OF THE HALOARCULA MARISMORTUI LARGE RIBOSOMAL SUBUNIT AT 2.4 ANGSTROM RESOLUTION===
 
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{{ABSTRACT_PUBMED_15184028}}
 
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==About this Structure==
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==REFINED CRYSTAL STRUCTURE OF THE HALOARCULA MARISMORTUI LARGE RIBOSOMAL SUBUNIT AT 2.4 ANGSTROM RESOLUTION==
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[[1s72]] is a 30 chain structure with sequence from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S72 OCA].
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<StructureSection load='1s72' size='340' side='right'caption='[[1s72]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1s72]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S72 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s72 OCA], [https://pdbe.org/1s72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s72 RCSB], [https://www.ebi.ac.uk/pdbsum/1s72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s72 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RL2_HALMA RL2_HALMA] One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).[HAMAP-Rule:MF_01320_A]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s7/1s72_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s72 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Large Ribosomal Subunit of Haloarcula|Large Ribosomal Subunit of Haloarcula]]
*[[Large Ribosomal Subunit of Haloarcula|Large Ribosomal Subunit of Haloarcula]]
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*[[Ribosomal protein L10|Ribosomal protein L10]]
 
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*[[Ribosomal protein L11|Ribosomal protein L11]]
 
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*[[Ribosomal protein L13|Ribosomal protein L13]]
 
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*[[Ribosomal protein L14|Ribosomal protein L14]]
 
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*[[Ribosomal protein L19|Ribosomal protein L19]]
 
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*[[Ribosomal protein L2|Ribosomal protein L2]]
 
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*[[Ribosomal protein L21|Ribosomal protein L21]]
 
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*[[Ribosomal protein L3|Ribosomal protein L3]]
 
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*[[Ribosomal protein L34|Ribosomal protein L34]]
 
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*[[Ribosomal protein L5|Ribosomal protein L5]]
 
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*[[Ribosomal protein L6|Ribosomal protein L6]]
 
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*[[Ribosomal protein L7|Ribosomal protein L7]]
 
*[[Ribosome|Ribosome]]
*[[Ribosome|Ribosome]]
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*[[User:Wayne Decatur/Haloarcula Large Ribosomal Subunit|User:Wayne Decatur/Haloarcula Large Ribosomal Subunit]]
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*[[Ribosome 3D structures|Ribosome 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:015184028</ref><ref group="xtra">PMID:016405997</ref><references group="xtra"/>
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[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
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[[Category: Klein, D J.]]
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[[Category: Large Structures]]
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[[Category: Moore, P B.]]
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[[Category: Klein DJ]]
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[[Category: Schmeing, T M.]]
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[[Category: Moore PB]]
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[[Category: Steitz, T A.]]
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[[Category: Schmeing TM]]
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[[Category: Protein-protein]]
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[[Category: Steitz TA]]
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[[Category: Protein-rna]]
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[[Category: Ribosome]]
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[[Category: Ribosome assembly]]
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[[Category: Rna-rna]]
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Current revision

REFINED CRYSTAL STRUCTURE OF THE HALOARCULA MARISMORTUI LARGE RIBOSOMAL SUBUNIT AT 2.4 ANGSTROM RESOLUTION

PDB ID 1s72

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