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2cxp
From Proteopedia
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| - | {{STRUCTURE_2cxp| PDB=2cxp | SCENE= }} | ||
| - | ===Crystal structure of mouse AMF / A5P complex=== | ||
| - | {{ABSTRACT_PUBMED_16375918}} | ||
| - | == | + | ==Crystal structure of mouse AMF / A5P complex== |
| - | [[2cxp]] is a 2 chain structure with sequence from [ | + | <StructureSection load='2cxp' size='340' side='right'caption='[[2cxp]], [[Resolution|resolution]] 1.70Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2cxp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CXP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A5P:ARABINOSE-5-PHOSPHATE'>A5P</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cxp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxp OCA], [https://pdbe.org/2cxp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cxp RCSB], [https://www.ebi.ac.uk/pdbsum/2cxp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cxp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/G6PI_MOUSE G6PI_MOUSE] Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/2cxp_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cxp ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | + | *[[Phosphoglucose isomerase 3D structures|Phosphoglucose isomerase 3D structures]] | |
| - | *[[Phosphoglucose isomerase|Phosphoglucose isomerase]] | + | __TOC__ |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | + | ||
| - | [[Category: | + | |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Funasaka | + | [[Category: Funasaka T]] |
| - | [[Category: Haga | + | [[Category: Haga A]] |
| - | [[Category: Hashimoto | + | [[Category: Hashimoto K]] |
| - | [[Category: Kusakabe | + | [[Category: Kusakabe Y]] |
| - | [[Category: Naba | + | [[Category: Naba N]] |
| - | [[Category: Nagase | + | [[Category: Nagase H]] |
| - | [[Category: Nakamura | + | [[Category: Nakamura KT]] |
| - | [[Category: Raz | + | [[Category: Raz A]] |
| - | [[Category: Shiraiwa | + | [[Category: Shiraiwa K]] |
| - | [[Category: Tanaka | + | [[Category: Tanaka N]] |
| - | + | ||
Current revision
Crystal structure of mouse AMF / A5P complex
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Categories: Large Structures | Mus musculus | Funasaka T | Haga A | Hashimoto K | Kusakabe Y | Naba N | Nagase H | Nakamura KT | Raz A | Shiraiwa K | Tanaka N
