1qd7
From Proteopedia
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- | {{STRUCTURE_1qd7| PDB=1qd7 | SCENE= }} | ||
- | ===PARTIAL MODEL FOR 30S RIBOSOMAL SUBUNIT=== | ||
- | {{ABSTRACT_PUBMED_10476960}} | ||
- | == | + | ==PARTIAL MODEL FOR 30S RIBOSOMAL SUBUNIT== |
- | [[1qd7]] is a 10 chain structure with sequence from [ | + | <StructureSection load='1qd7' size='340' side='right'caption='[[1qd7]], [[Resolution|resolution]] 5.50Å' scene=''> |
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[1qd7]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QD7 FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 5.5Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N:ANY+5-MONOPHOSPHATE+NUCLEOTIDE'>N</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qd7 OCA], [https://pdbe.org/1qd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qd7 RCSB], [https://www.ebi.ac.uk/pdbsum/1qd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qd7 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/RS4_GEOSE RS4_GEOSE] One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity).[HAMAP-Rule:MF_01306_B] With S5 and S12 plays an important role in translational accuracy (By similarity).[HAMAP-Rule:MF_01306_B] | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qd/1qd7_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qd7 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | <div style="background-color:#fffaf0;"> | ||
+ | == Publication Abstract from PubMed == | ||
+ | The 30S ribosomal subunit binds messenger RNA and the anticodon stem-loop of transfer RNA during protein synthesis. A crystallographic analysis of the structure of the subunit from the bacterium Thermus thermophilus is presented. At a resolution of 5.5 A, the phosphate backbone of the ribosomal RNA is visible, as are the alpha-helices of the ribosomal proteins, enabling double-helical regions of RNA to be identified throughout the subunit, all seven of the small-subunit proteins of known crystal structure to be positioned in the electron density map, and the fold of the entire central domain of the small-subunit ribosomal RNA to be determined. | ||
+ | |||
+ | Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.,Clemons WM Jr, May JL, Wimberly BT, McCutcheon JP, Capel MS, Ramakrishnan V Nature. 1999 Aug 26;400(6747):833-40. PMID:10476960<ref>PMID:10476960</ref> | ||
+ | |||
+ | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
+ | </div> | ||
+ | <div class="pdbe-citations 1qd7" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
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*[[Ribosomal protein S7|Ribosomal protein S7]] | *[[Ribosomal protein S7|Ribosomal protein S7]] | ||
*[[Ribosomal protein S8|Ribosomal protein S8]] | *[[Ribosomal protein S8|Ribosomal protein S8]] | ||
- | + | == References == | |
- | + | <references/> | |
- | == | + | __TOC__ |
- | < | + | </StructureSection> |
+ | [[Category: Large Structures]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
- | [[Category: Capel | + | [[Category: Capel MS]] |
- | [[Category: Clemons | + | [[Category: Clemons Jr WM]] |
- | [[Category: May | + | [[Category: May JLC]] |
- | [[Category: McCutcheon | + | [[Category: McCutcheon JP]] |
- | [[Category: Ramakrishnan | + | [[Category: Ramakrishnan V]] |
- | [[Category: Wimberly | + | [[Category: Wimberly BT]] |
- | + | ||
- | + | ||
- | + |
Current revision
PARTIAL MODEL FOR 30S RIBOSOMAL SUBUNIT
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