1ffk
From Proteopedia
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| - | {{STRUCTURE_1ffk| PDB=1ffk | SCENE= }} | ||
| - | ===CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION=== | ||
| - | {{ABSTRACT_PUBMED_10937989}} | ||
| - | == | + | ==CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION== |
| - | [[1ffk]] is a | + | <StructureSection load='1ffk' size='340' side='right'caption='[[1ffk]], [[Resolution|resolution]] 2.40Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1ffk]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. The October 2000 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Ribosome'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2000_10 10.2210/rcsb_pdb/mom_2000_10]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FFK FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ffk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffk OCA], [https://pdbe.org/1ffk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ffk RCSB], [https://www.ebi.ac.uk/pdbsum/1ffk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ffk ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RL2_HALMA RL2_HALMA] One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome (By similarity).[HAMAP-Rule:MF_01320_A] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/1ffk_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ffk ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Large Ribosomal Subunit of Haloarcula|Large Ribosomal Subunit of Haloarcula]] | *[[Large Ribosomal Subunit of Haloarcula|Large Ribosomal Subunit of Haloarcula]] | ||
| - | *[[Nobel Prizes for 3D Molecular Structure|Nobel Prizes for 3D Molecular Structure]] | ||
| - | *[[Ribosomal protein L10|Ribosomal protein L10]] | ||
| - | *[[Ribosomal protein L13|Ribosomal protein L13]] | ||
| - | *[[Ribosomal protein L14|Ribosomal protein L14]] | ||
| - | *[[Ribosomal protein L15|Ribosomal protein L15]] | ||
| - | *[[Ribosomal protein L18|Ribosomal protein L18]] | ||
| - | *[[Ribosomal protein L19|Ribosomal protein L19]] | ||
| - | *[[Ribosomal protein L2|Ribosomal protein L2]] | ||
| - | *[[Ribosomal protein L21|Ribosomal protein L21]] | ||
| - | *[[Ribosomal protein L22|Ribosomal protein L22]] | ||
| - | *[[Ribosomal protein L23|Ribosomal protein L23]] | ||
| - | *[[Ribosomal protein L24|Ribosomal protein L24]] | ||
| - | *[[Ribosomal protein L29|Ribosomal protein L29]] | ||
| - | *[[Ribosomal protein L3|Ribosomal protein L3]] | ||
| - | *[[Ribosomal protein L30|Ribosomal protein L30]] | ||
| - | *[[Ribosomal protein L34|Ribosomal protein L34]] | ||
| - | *[[Ribosomal protein L4|Ribosomal protein L4]] | ||
| - | *[[Ribosomal protein L5|Ribosomal protein L5]] | ||
| - | *[[Ribosomal protein L6|Ribosomal protein L6]] | ||
| - | *[[Ribosomal protein L7|Ribosomal protein L7]] | ||
*[[Ribosome|Ribosome]] | *[[Ribosome|Ribosome]] | ||
| - | *[[ | + | *[[Ribosome 3D structures|Ribosome 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Haloarcula marismortui]] | [[Category: Haloarcula marismortui]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
[[Category: Ribosome]] | [[Category: Ribosome]] | ||
| - | [[Category: Ban | + | [[Category: Ban N]] |
| - | [[Category: Hansen | + | [[Category: Hansen J]] |
| - | [[Category: Moore | + | [[Category: Moore PB]] |
| - | [[Category: Nissen | + | [[Category: Nissen P]] |
| - | [[Category: Steitz | + | [[Category: Steitz TA]] |
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Current revision
CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION
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