4djf

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{{STRUCTURE_4djf| PDB=4djf | SCENE= }}
 
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===Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate and Ti(III) citrate reductant===
 
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{{ABSTRACT_PUBMED_22419154}}
 
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==About this Structure==
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==Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate and Ti(III) citrate reductant==
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[[4djf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Moorella_thermoacetica Moorella thermoacetica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DJF OCA].
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<StructureSection load='4djf' size='340' side='right'caption='[[4djf]], [[Resolution|resolution]] 3.03&Aring;' scene=''>
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== Structural highlights ==
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==See Also==
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<table><tr><td colspan='2'>[[4djf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Moorella_thermoacetica Moorella thermoacetica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DJF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DJF FirstGlance]. <br>
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*[[Suggestions for new articles|Suggestions for new articles]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.03&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C2F:5-METHYL-5,6,7,8-TETRAHYDROFOLIC+ACID'>C2F</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=COB:CO-METHYLCOBALAMIN'>COB</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4djf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4djf OCA], [https://pdbe.org/4djf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4djf RCSB], [https://www.ebi.ac.uk/pdbsum/4djf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4djf ProSAT]</span></td></tr>
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<ref group="xtra">PMID:022419154</ref><references group="xtra"/>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACSE_MOOTH ACSE_MOOTH] Methyltransferase that mediates the transfer of a N5-methyl group of (6S)-methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein in the anaerobic acetyl-CoA pathway (Wood-Ljungdahl pathway) of carbon monoxide and carbon dioxide fixation.<ref>PMID:17172470</ref> <ref>PMID:22419154</ref> <ref>PMID:7928975</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Moorella thermoacetica]]
[[Category: Moorella thermoacetica]]
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[[Category: Drennan, C L.]]
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[[Category: Drennan CL]]
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[[Category: Kung, Y.]]
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[[Category: Kung Y]]
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[[Category: B12-dependent methyltransferase]]
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[[Category: Rossmann fold]]
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[[Category: Tim barrel]]
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[[Category: Transferase-vitamin-binding protein complex]]
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Current revision

Crystal structure of folate-bound corrinoid iron-sulfur protein (CFeSP) in complex with its methyltransferase (MeTr), co-crystallized with folate and Ti(III) citrate reductant

PDB ID 4djf

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