2baz
From Proteopedia
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| - | [[Image:2baz.gif|left|200px]]<br /><applet load="2baz" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2baz, resolution 2.300Å" /> | ||
| - | '''Structure of YosS, a putative dUTPase from Bacillus subtilis'''<br /> | ||
| - | == | + | ==Structure of YosS, a putative dUTPase from Bacillus subtilis== |
| - | + | <StructureSection load='2baz' size='340' side='right'caption='[[2baz]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2baz]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BAZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2baz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2baz OCA], [https://pdbe.org/2baz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2baz RCSB], [https://www.ebi.ac.uk/pdbsum/2baz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2baz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/YOSS_BACSU YOSS_BACSU] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/2baz_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2baz ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Liang | + | [[Category: Liang Y-H]] |
| - | [[Category: Su | + | [[Category: Su X-D]] |
| - | [[Category: Wang | + | [[Category: Wang J]] |
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Current revision
Structure of YosS, a putative dUTPase from Bacillus subtilis
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