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1k4q
From Proteopedia
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| - | {{STRUCTURE_1k4q| PDB=1k4q | SCENE= }} | ||
| - | ===Human Glutathione Reductase Inactivated by Peroxynitrite=== | ||
| - | {{ABSTRACT_PUBMED_11705998}} | ||
| - | == | + | ==Human Glutathione Reductase Inactivated by Peroxynitrite== |
| - | [[1k4q]] is a 1 chain structure with sequence from [ | + | <StructureSection load='1k4q' size='340' side='right'caption='[[1k4q]], [[Resolution|resolution]] 1.90Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1k4q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K4Q FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NIY:META-NITRO-TYROSINE'>NIY</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k4q OCA], [https://pdbe.org/1k4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k4q RCSB], [https://www.ebi.ac.uk/pdbsum/1k4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k4q ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GSHR_HUMAN GSHR_HUMAN] Maintains high levels of reduced glutathione in the cytosol. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/1k4q_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k4q ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Glutathione Reductase|Glutathione Reductase]] | *[[Glutathione Reductase|Glutathione Reductase]] | ||
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Arteel | + | [[Category: Large Structures]] |
| - | [[Category: Becker | + | [[Category: Arteel GE]] |
| - | [[Category: Boehme | + | [[Category: Becker K]] |
| - | [[Category: Karplus | + | [[Category: Boehme CC]] |
| - | [[Category: Savvides | + | [[Category: Karplus PA]] |
| - | [[Category: Scheiwein | + | [[Category: Savvides SN]] |
| - | [[Category: Schirmer | + | [[Category: Scheiwein M]] |
| - | + | [[Category: Schirmer RH]] | |
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Current revision
Human Glutathione Reductase Inactivated by Peroxynitrite
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