This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3sn6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:02, 14 March 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_3sn6| PDB=3sn6 | SCENE= }}
 
-
===Crystal structure of the beta2 adrenergic receptor-Gs protein complex===
 
-
{{ABSTRACT_PUBMED_21772288}}
 
-
==About this Structure==
+
==Crystal structure of the beta2 adrenergic receptor-Gs protein complex==
-
[[3sn6]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4], [http://en.wikipedia.org/wiki/Lama_glama Lama glama] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SN6 OCA].
+
<StructureSection load='3sn6' size='340' side='right'caption='[[3sn6]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3sn6]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SN6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SN6 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P0G:8-[(1R)-2-{[1,1-DIMETHYL-2-(2-METHYLPHENYL)ETHYL]AMINO}-1-HYDROXYETHYL]-5-HYDROXY-2H-1,4-BENZOXAZIN-3(4H)-ONE'>P0G</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sn6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sn6 OCA], [https://pdbe.org/3sn6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sn6 RCSB], [https://www.ebi.ac.uk/pdbsum/3sn6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sn6 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/GNAS2_BOVIN GNAS2_BOVIN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli.
==See Also==
==See Also==
*[[Adrenergic receptor|Adrenergic receptor]]
*[[Adrenergic receptor|Adrenergic receptor]]
-
*[[Beta-2 Adrenergic Receptor|Beta-2 Adrenergic Receptor]]
+
*[[Adrenergic receptor 3D structures|Adrenergic receptor 3D structures]]
 +
*[[Antibody 3D structures|Antibody 3D structures]]
*[[G protein-coupled receptor|G protein-coupled receptor]]
*[[G protein-coupled receptor|G protein-coupled receptor]]
-
*[[GTP-binding protein|GTP-binding protein]]
+
*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
-
*[[Hen Egg-White (HEW) Lysozyme|Hen Egg-White (HEW) Lysozyme]]
+
*[[Hormone|Hormone]]
*[[Hormone|Hormone]]
-
*[[Nobel Prizes for 3D Molecular Structure|Nobel Prizes for 3D Molecular Structure]]
+
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
-
*[[Suggestions for new articles|Suggestions for new articles]]
+
*[[Neurotransmitters|Neurotransmitters]]
-
*[[User:Wayne Decatur/UNH BCHEM833 Structural Analysis Workshop Session Fall 2012|User:Wayne Decatur/UNH BCHEM833 Structural Analysis Workshop Session Fall 2012]]
+
*[[Transducin 3D structures|Transducin 3D structures]]
-
*[[User:Wayne Decatur/UNH BCHEM833 Structural Proteomics Introductory Lecture Fall 2012|User:Wayne Decatur/UNH BCHEM833 Structural Proteomics Introductory Lecture Fall 2012]]
+
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:021772288</ref><references group="xtra"/>
+
[[Category: Bos taurus]]
[[Category: Bos taurus]]
-
[[Category: Enterobacteria phage t4]]
+
[[Category: Escherichia virus T4]]
 +
[[Category: Homo sapiens]]
[[Category: Lama glama]]
[[Category: Lama glama]]
-
[[Category: Lysozyme]]
+
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
-
[[Category: Caffrey, M.]]
+
[[Category: Caffrey M]]
-
[[Category: Calinski, D.]]
+
[[Category: Calinski D]]
-
[[Category: Chae, P S.]]
+
[[Category: Chae PS]]
-
[[Category: Chung, K Y.]]
+
[[Category: Chung KY]]
-
[[Category: DeVree, B T.]]
+
[[Category: DeVree BT]]
-
[[Category: Gellman, S H.]]
+
[[Category: Gellman SH]]
-
[[Category: Kobilka, B K.]]
+
[[Category: Kobilka BK]]
-
[[Category: Kobilka, T S.]]
+
[[Category: Kobilka TS]]
-
[[Category: Kruse, A C.]]
+
[[Category: Kruse AC]]
-
[[Category: Lyons, J A.]]
+
[[Category: Lyons JA]]
-
[[Category: Mathiesen, J M.]]
+
[[Category: Mathiesen JM]]
-
[[Category: Pardon, E.]]
+
[[Category: Pardon E]]
-
[[Category: Rasmussen, S G.F.]]
+
[[Category: Rasmussen SGF]]
-
[[Category: Shah, S T.A.]]
+
[[Category: Shah STA]]
-
[[Category: Skiniotis, G.]]
+
[[Category: Skiniotis G]]
-
[[Category: Steyaert, J.]]
+
[[Category: Steyaert J]]
-
[[Category: Sunahara, R K.]]
+
[[Category: Sunahara RK]]
-
[[Category: Thian, F S.]]
+
[[Category: Thian FS]]
-
[[Category: Weis, W I.]]
+
[[Category: Weis WI]]
-
[[Category: Zou, Y.]]
+
[[Category: Zou Y]]
-
[[Category: G protein signaling]]
+
-
[[Category: G protein-coupled receptor]]
+
-
[[Category: Gpcr]]
+
-
[[Category: Nanobody]]
+
-
[[Category: Seven transmembrane receptor]]
+
-
[[Category: Signal transduction]]
+
-
[[Category: Signaling protein-hydrolase complex]]
+

Current revision

Crystal structure of the beta2 adrenergic receptor-Gs protein complex

PDB ID 3sn6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3sn6"
Personal tools