1zwz
From Proteopedia
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| - | {{STRUCTURE_1zwz| PDB=1zwz | SCENE= }} | ||
| - | ===Structural comparison of Yeast snoRNP and splicesomal protein snu13p with its homologs=== | ||
| - | {{ABSTRACT_PUBMED_15963469}} | ||
| - | == | + | ==Structural comparison of Yeast snoRNP and splicesomal protein snu13p with its homologs== |
| - | [[1zwz]] is a 2 chain structure with sequence from [ | + | <StructureSection load='1zwz' size='340' side='right'caption='[[1zwz]], [[Resolution|resolution]] 1.90Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1zwz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZWZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZWZ FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zwz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zwz OCA], [https://pdbe.org/1zwz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zwz RCSB], [https://www.ebi.ac.uk/pdbsum/1zwz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zwz ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | <ref | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SNU13_YEAST SNU13_YEAST] Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs.<ref>PMID:11081632</ref> <ref>PMID:12215523</ref> <ref>PMID:14730029</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zw/1zwz_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zwz ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Li | + | [[Category: Li H]] |
| - | [[Category: Oruganti | + | [[Category: Oruganti S]] |
| - | [[Category: Zhang | + | [[Category: Zhang Y]] |
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Current revision
Structural comparison of Yeast snoRNP and splicesomal protein snu13p with its homologs
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