2b6p
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_2b6p| PDB=2b6p | SCENE= }} | ||
| - | ===X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state=== | ||
| - | {{ABSTRACT_PUBMED_15377788}} | ||
| - | == | + | ==X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state== |
| - | [[2b6p]] is a 1 chain structure with sequence from [ | + | <StructureSection load='2b6p' size='340' side='right'caption='[[2b6p]], [[Resolution|resolution]] 2.40Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2b6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B6P FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6p OCA], [https://pdbe.org/2b6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b6p RCSB], [https://www.ebi.ac.uk/pdbsum/2b6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b6p ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MIP_BOVIN MIP_BOVIN] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:16319884</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b6p_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b6p ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Aquaporin|Aquaporin]] | + | *[[Aquaporin 3D structures|Aquaporin 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
| - | [[Category: Cheng | + | [[Category: Large Structures]] |
| - | [[Category: Fujiyoshi | + | [[Category: Cheng Y]] |
| - | [[Category: Gonen | + | [[Category: Fujiyoshi Y]] |
| - | [[Category: Harrison | + | [[Category: Gonen T]] |
| - | [[Category: Hiroaki | + | [[Category: Harrison SC]] |
| - | [[Category: Sliz | + | [[Category: Hiroaki Y]] |
| - | [[Category: Walz | + | [[Category: Sliz P]] |
| - | + | [[Category: Walz T]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state
| |||||||||||
Categories: Bos taurus | Large Structures | Cheng Y | Fujiyoshi Y | Gonen T | Harrison SC | Hiroaki Y | Sliz P | Walz T
