1e82
From Proteopedia
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| - | {{STRUCTURE_1e82| PDB=1e82 | SCENE= }} | ||
| - | ===ENDOTHIAPEPSIN COMPLEX WITH RENIN INHIBITOR MERCK-KGAA-EMD59601=== | ||
| - | == | + | ==Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD59601== |
| - | [[1e82]] is a 1 chain structure with sequence from [ | + | <StructureSection load='1e82' size='340' side='right'caption='[[1e82]], [[Resolution|resolution]] 2.05Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1e82]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E82 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=M90:(2S)-1-{[(2R)-1-{[(2S,3R)-1-CYCLOHEXYL-3-HYDROXY-4-(PYRIDIN-4-YLOXY)BUTAN-2-YL]AMINO}-3-(METHYLSULFANYL)-1-OXOPROPAN-2-YL]AMINO}-1-OXO-3-PHENYLPROPAN-2-YL+4-AMINOPIPERIDINE-1-CARBOXYLATE'>M90</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e82 OCA], [https://pdbe.org/1e82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e82 RCSB], [https://www.ebi.ac.uk/pdbsum/1e82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e82 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e8/1e82_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e82 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Pepsin|Pepsin]] | *[[Pepsin|Pepsin]] | ||
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Cryphonectria parasitica]] | [[Category: Cryphonectria parasitica]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Cooper | + | [[Category: Cooper JB]] |
| - | [[Category: Raddatz | + | [[Category: Raddatz P]] |
| - | [[Category: Read | + | [[Category: Read JA]] |
| - | [[Category: Rippmann | + | [[Category: Rippmann F]] |
| - | [[Category: Toldo | + | [[Category: Toldo L]] |
| - | + | ||
| - | + | ||
Current revision
Endothiapepsin complex with renin inhibitor MERCK-KGAA-EMD59601
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