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3btn

From Proteopedia

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{{STRUCTURE_3btn| PDB=3btn | SCENE= }}
 
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===Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein===
 
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{{ABSTRACT_PUBMED_18369191}}
 
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==About this Structure==
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==Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein==
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[[3btn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BTN OCA].
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<StructureSection load='3btn' size='340' side='right'caption='[[3btn]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3btn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BTN FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3btn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3btn OCA], [https://pdbe.org/3btn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3btn RCSB], [https://www.ebi.ac.uk/pdbsum/3btn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3btn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AZIN1_MOUSE AZIN1_MOUSE] Inhibits antizyme-dependent ODC degradation by binding to antizyme with greater affinity. Regulates cellular polyamine homeostasis.<ref>PMID:10698696</ref> <ref>PMID:18369191</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bt/3btn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3btn ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Antizyme Inhibitor|Antizyme Inhibitor]]
*[[Antizyme Inhibitor|Antizyme Inhibitor]]
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*[[Antizyme inhibitor 3D structures|Antizyme inhibitor 3D structures]]
*[[Ornithine decarboxylase|Ornithine decarboxylase]]
*[[Ornithine decarboxylase|Ornithine decarboxylase]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:018369191</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Albeck, S.]]
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[[Category: Albeck S]]
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[[Category: Dym, O.]]
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[[Category: Dym O]]
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[[Category: ISPC, Israel Structural Proteomics Center.]]
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[[Category: Kahana C]]
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[[Category: Kahana, C.]]
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[[Category: Unger T]]
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[[Category: Unger, T.]]
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[[Category: Biosynthetic protein]]
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[[Category: ISPC]]
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[[Category: Israel Structural Proteomics Center]]
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[[Category: Polyamine biosynthesis]]
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[[Category: Structural genomic]]
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[[Category: Tim-like a/b barrel domain and a sheet domain]]
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Current revision

Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein

PDB ID 3btn

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