3btn
From Proteopedia
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| - | {{STRUCTURE_3btn| PDB=3btn | SCENE= }} | ||
| - | ===Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein=== | ||
| - | {{ABSTRACT_PUBMED_18369191}} | ||
| - | == | + | ==Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein== |
| - | [[3btn]] is a 2 chain structure with sequence from [ | + | <StructureSection load='3btn' size='340' side='right'caption='[[3btn]], [[Resolution|resolution]] 2.05Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3btn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BTN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BTN FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3btn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3btn OCA], [https://pdbe.org/3btn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3btn RCSB], [https://www.ebi.ac.uk/pdbsum/3btn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3btn ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AZIN1_MOUSE AZIN1_MOUSE] Inhibits antizyme-dependent ODC degradation by binding to antizyme with greater affinity. Regulates cellular polyamine homeostasis.<ref>PMID:10698696</ref> <ref>PMID:18369191</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bt/3btn_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3btn ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Antizyme Inhibitor|Antizyme Inhibitor]] | *[[Antizyme Inhibitor|Antizyme Inhibitor]] | ||
| + | *[[Antizyme inhibitor 3D structures|Antizyme inhibitor 3D structures]] | ||
*[[Ornithine decarboxylase|Ornithine decarboxylase]] | *[[Ornithine decarboxylase|Ornithine decarboxylase]] | ||
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Albeck | + | [[Category: Albeck S]] |
| - | [[Category: Dym | + | [[Category: Dym O]] |
| - | + | [[Category: Kahana C]] | |
| - | [[Category: Kahana | + | [[Category: Unger T]] |
| - | [[Category: Unger | + | |
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Current revision
Crystal structure of antizyme inhibitor, an ornithine decarboxylase homologous protein
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Categories: Large Structures | Mus musculus | Albeck S | Dym O | Kahana C | Unger T
