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1e08
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| - | {{STRUCTURE_1e08| PDB=1e08 | SCENE= }} | ||
| - | ===STRUCTURAL MODEL OF THE [FE]-HYDROGENASE/CYTOCHROME C553 COMPLEX COMBINING NMR AND SOFT-DOCKING=== | ||
| - | {{ABSTRACT_PUBMED_10748163}} | ||
| - | == | + | ==Structural model of the [Fe]-Hydrogenase/cytochrome c553 complex combining NMR and soft-docking== |
| - | [[1e08]] is a 3 chain structure with sequence from [ | + | <StructureSection load='1e08' size='340' side='right'caption='[[1e08]]' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1e08]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_desulfuricans Desulfovibrio desulfuricans] and [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._Hildenborough Desulfovibrio vulgaris str. Hildenborough]. The March 2009 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Hydrogenase'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2009_3 10.2210/rcsb_pdb/mom_2009_3]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E08 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Hybrid , Solution NMR , Theoretical Model</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMO:CARBON+MONOXIDE'>CMO</scene>, <scene name='pdbligand=CYN:CYANIDE+ION'>CYN</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PDT:1,3-PROPANEDITHIOL'>PDT</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e08 OCA], [https://pdbe.org/1e08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e08 RCSB], [https://www.ebi.ac.uk/pdbsum/1e08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e08 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHFL_DESVH PHFL_DESVH] May be involved in hydrogen uptake for the reduction of sulfate to hydrogen sulfide in an electron transport chain. Cytochrome c3 is likely to be the physiological electron carrier for the enzyme. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e0/1e08_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1e08 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Cytochrome | + | *[[Cytochrome C 3D structures|Cytochrome C 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Desulfovibrio desulfuricans]] | [[Category: Desulfovibrio desulfuricans]] | ||
| - | [[Category: Desulfovibrio vulgaris]] | + | [[Category: Desulfovibrio vulgaris str. Hildenborough]] |
[[Category: Hydrogenase]] | [[Category: Hydrogenase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
| - | [[Category: Bornet | + | [[Category: Bornet O]] |
| - | [[Category: Czjzek | + | [[Category: Czjzek M]] |
| - | [[Category: Fontecilla-Camps | + | [[Category: Fontecilla-Camps JC]] |
| - | [[Category: Guerlesquin | + | [[Category: Guerlesquin F]] |
| - | [[Category: Hatchikian | + | [[Category: Hatchikian CE]] |
| - | [[Category: Morelli | + | [[Category: Morelli X]] |
| - | [[Category: Moura | + | [[Category: Moura JJG]] |
| - | [[Category: Palma | + | [[Category: Palma NP]] |
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Current revision
Structural model of the [Fe]-Hydrogenase/cytochrome c553 complex combining NMR and soft-docking
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