4jjh
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the D1 domain from human Nectin-4 extracellular fragment [PSI-NYSGRC-005624]== | |
| + | <StructureSection load='4jjh' size='340' side='right'caption='[[4jjh]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4jjh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JJH FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jjh OCA], [https://pdbe.org/4jjh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jjh RCSB], [https://www.ebi.ac.uk/pdbsum/4jjh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jjh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/NECT4_HUMAN NECT4_HUMAN] Ectodermal dysplasia-pili torti-cutaneous syndactyly syndrome. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NECT4_HUMAN NECT4_HUMAN] Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells. (Microbial infection) Acts as a receptor for measles virus.<ref>PMID:22048310</ref> <ref>PMID:23202587</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Poliovirus receptor-related protein|Poliovirus receptor-related protein]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ahmed M]] | ||
| + | [[Category: Almo SC]] | ||
| + | [[Category: Banu R]] | ||
| + | [[Category: Bhosle R]] | ||
| + | [[Category: Bonanno J]] | ||
| + | [[Category: Calarese D]] | ||
| + | [[Category: Celikigil A]] | ||
| + | [[Category: Chamala S]] | ||
| + | [[Category: Chan MK]] | ||
| + | [[Category: Chowdhury S]] | ||
| + | [[Category: Fiser A]] | ||
| + | [[Category: Garforth S]] | ||
| + | [[Category: Glenn AS]] | ||
| + | [[Category: Hillerich B]] | ||
| + | [[Category: Khafizov K]] | ||
| + | [[Category: Kumar PR]] | ||
| + | [[Category: Love J]] | ||
| + | [[Category: Nathenson SG]] | ||
| + | [[Category: Patel H]] | ||
| + | [[Category: Seidel R]] | ||
| + | [[Category: Stead M]] | ||
| + | [[Category: Toro R]] | ||
Current revision
Crystal structure of the D1 domain from human Nectin-4 extracellular fragment [PSI-NYSGRC-005624]
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Categories: Homo sapiens | Large Structures | Ahmed M | Almo SC | Banu R | Bhosle R | Bonanno J | Calarese D | Celikigil A | Chamala S | Chan MK | Chowdhury S | Fiser A | Garforth S | Glenn AS | Hillerich B | Khafizov K | Kumar PR | Love J | Nathenson SG | Patel H | Seidel R | Stead M | Toro R
