4gzu
From Proteopedia
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| - | {{STRUCTURE_4gzu| PDB=4gzu | SCENE= }} | ||
| - | ===Crystal strucure of the DH-PH-PH domain of FARP2=== | ||
| - | {{ABSTRACT_PUBMED_23375260}} | ||
| - | == | + | ==Crystal structure of the DH-PH-PH domain of FARP2== |
| - | [[4gzu]] is a 2 chain structure with sequence from [ | + | <StructureSection load='4gzu' size='340' side='right'caption='[[4gzu]], [[Resolution|resolution]] 3.20Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4gzu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GZU FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gzu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gzu OCA], [https://pdbe.org/4gzu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gzu RCSB], [https://www.ebi.ac.uk/pdbsum/4gzu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gzu ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FARP2_MOUSE FARP2_MOUSE] Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton.<ref>PMID:12351724</ref> <ref>PMID:16286926</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: He | + | [[Category: He X]] |
| - | [[Category: Zhang | + | [[Category: Zhang X]] |
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Current revision
Crystal structure of the DH-PH-PH domain of FARP2
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