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4e02
From Proteopedia
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| - | {{STRUCTURE_4e02| PDB=4e02 | SCENE= }} | ||
| - | ===Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/(S)-2-chloro-3-phenylpropanoic acid complex with AMPPNP=== | ||
| - | == | + | ==Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/(S)-2-chloro-3-phenylpropanoic acid complex with AMPPNP== |
| - | [[4e02]] is a 1 chain structure with sequence from [ | + | <StructureSection load='4e02' size='340' side='right'caption='[[4e02]], [[Resolution|resolution]] 2.15Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4e02]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E02 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E02 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1547Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=WJ1:(S)-2-CHLORO-3-PHENYLPROPANOIC+ACID'>WJ1</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e02 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e02 OCA], [https://pdbe.org/4e02 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e02 RCSB], [https://www.ebi.ac.uk/pdbsum/4e02 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e02 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BCKD_RAT BCKD_RAT] Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
| - | [[Category: Chuang | + | [[Category: Chuang DT]] |
| - | [[Category: Chuang | + | [[Category: Chuang JL]] |
| - | [[Category: Gui | + | [[Category: Gui WJ]] |
| - | [[Category: Li | + | [[Category: Li J]] |
| - | [[Category: Tso | + | [[Category: Tso SC]] |
| - | [[Category: Wynn | + | [[Category: Wynn RM]] |
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Current revision
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/(S)-2-chloro-3-phenylpropanoic acid complex with AMPPNP
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Categories: Large Structures | Rattus norvegicus | Chuang DT | Chuang JL | Gui WJ | Li J | Tso SC | Wynn RM
