3ii0

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{{STRUCTURE_3ii0| PDB=3ii0 | SCENE= }}
 
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===Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1)===
 
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==About this Structure==
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==Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1)==
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[[3ii0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3II0 OCA].
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<StructureSection load='3ii0' size='340' side='right'caption='[[3ii0]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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[[Category: Aspartate transaminase]]
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3ii0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3II0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3II0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=TAR:D(-)-TARTARIC+ACID'>TAR</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ii0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ii0 OCA], [https://pdbe.org/3ii0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ii0 RCSB], [https://www.ebi.ac.uk/pdbsum/3ii0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ii0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AATC_HUMAN AATC_HUMAN] Plays a key role in amino acid metabolism (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ii/3ii0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ii0 ConSurf].
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<div style="clear:both"></div>
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==See Also==
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*[[Aspartate aminotransferase 3D structures|Aspartate aminotransferase 3D structures]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bountra, C.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bray, J E.]]
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[[Category: Bountra C]]
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[[Category: Chaikuad, A.]]
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[[Category: Bray JE]]
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[[Category: Cooper, C.]]
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[[Category: Chaikuad A]]
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[[Category: Delft, F von.]]
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[[Category: Cooper C]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Kavanagh, K L.]]
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[[Category: Kavanagh KL]]
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[[Category: Muniz, J.]]
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[[Category: Muniz J]]
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[[Category: Oppermann, U.]]
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[[Category: Oppermann U]]
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[[Category: Pilka, E.]]
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[[Category: Pilka E]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Ugochukwu E]]
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[[Category: Ugochukwu, E.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: Yue WW]]
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[[Category: Yue, W W.]]
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[[Category: Von Delft F]]
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[[Category: Amino acid metabolism]]
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[[Category: Aminotransferase]]
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[[Category: Aspartate aminotransferase 1]]
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[[Category: Glutamate oxaloacetate transaminase 1]]
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[[Category: Phosphoprotein]]
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[[Category: Pyridoxal phosphate]]
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[[Category: Pyridoxal phosphate-dependent enzyme]]
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[[Category: Sgc]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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[[Category: Transferase]]
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[[Category: Urea and tricarboxylic acid cycle]]
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Current revision

Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1)

PDB ID 3ii0

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