3i2z

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{{STRUCTURE_3i2z| PDB=3i2z | SCENE= }}
 
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===Structure of cold shock protein E from Salmonella typhimurium===
 
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{{ABSTRACT_PUBMED_20054119}}
 
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==About this Structure==
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==Structure of cold shock protein E from Salmonella typhimurium==
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[[3i2z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I2Z OCA].
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<StructureSection load='3i2z' size='340' side='right'caption='[[3i2z]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3i2z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I2Z FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i2z OCA], [https://pdbe.org/3i2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i2z RCSB], [https://www.ebi.ac.uk/pdbsum/3i2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i2z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7CQZ5_SALTY Q7CQZ5_SALTY]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i2/3i2z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i2z ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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In prokaryotic organisms, cold shock triggers the production of a small highly conserved family of cold-shock proteins (CSPs). CSPs have been well studied structurally and functionally in Escherichia coli and Bacillus subtilis, but Salmonella typhimurium CSPs remain relatively uncharacterized. In S. typhimurium, six homologous CSPs have been identified: StCspA-E and StCspH. The crystal structure of cold-shock protein E from S. typhimurium (StCspE) has been determined at 1.1 A resolution and has an R factor of 0.203 after refinement. The three-dimensional structure is similar to those of previously determined CSPs and is composed of five antiparallel beta-strands forming a classic OB fold/five-stranded beta-barrel. This first structure of a CSP from S. typhimurium provides new insight into the cold-shock response of this bacterium.
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==Reference==
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Crystallization and X-ray structure of cold-shock protein E from Salmonella typhimurium.,Morgan HP, Wear MA, McNae I, Gallagher MP, Walkinshaw MD Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt, 12):1240-5. Epub 2009 Nov 27. PMID:20054119<ref>PMID:20054119</ref>
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<ref group="xtra">PMID:020054119</ref><references group="xtra"/>
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[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Gallagher, M.]]
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</div>
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[[Category: McNae, I.]]
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<div class="pdbe-citations 3i2z" style="background-color:#fffaf0;"></div>
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[[Category: Morgan, H P.]]
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== References ==
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[[Category: Walkinshaw, M D.]]
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<references/>
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[[Category: Wear, M A.]]
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__TOC__
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[[Category: Beta barrel]]
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</StructureSection>
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[[Category: Dna binding protein/transcription]]
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[[Category: Large Structures]]
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[[Category: Gene regulation]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Gallagher M]]
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[[Category: McNae I]]
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[[Category: Morgan HP]]
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[[Category: Walkinshaw MD]]
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[[Category: Wear MA]]

Current revision

Structure of cold shock protein E from Salmonella typhimurium

PDB ID 3i2z

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