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1gbq
From Proteopedia
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| - | {{STRUCTURE_1gbq| PDB=1gbq | SCENE= }} | ||
| - | ===SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE=== | ||
| - | {{ABSTRACT_PUBMED_9135122}} | ||
| - | == | + | ==SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE== |
| - | [[1gbq]] is a 2 chain structure with sequence from [ | + | <StructureSection load='1gbq' size='340' side='right'caption='[[1gbq]]' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1gbq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GBQ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gbq OCA], [https://pdbe.org/1gbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gbq RCSB], [https://www.ebi.ac.uk/pdbsum/1gbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gbq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SOS1_MOUSE SOS1_MOUSE] Promotes the exchange of Ras-bound GDP by GTP (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gb/1gbq_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gbq ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Growth factor receptor-bound | + | *[[Growth factor receptor-bound proteins 3D structures|Growth factor receptor-bound proteins 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Friedrichs | + | [[Category: Friedrichs MS]] |
| - | [[Category: Goldfarb | + | [[Category: Goldfarb V]] |
| - | [[Category: Lee | + | [[Category: Lee V]] |
| - | [[Category: Mapelli | + | [[Category: Mapelli C]] |
| - | [[Category: Meyers | + | [[Category: Meyers CA]] |
| - | [[Category: Mueller | + | [[Category: Mueller L]] |
| - | [[Category: Wittekind | + | [[Category: Wittekind M]] |
| - | + | ||
Current revision
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
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Categories: Large Structures | Mus musculus | Friedrichs MS | Goldfarb V | Lee V | Mapelli C | Meyers CA | Mueller L | Wittekind M
