This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3ir3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:56, 6 September 2023) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_3ir3| PDB=3ir3 | SCENE= }}
 
-
===Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)===
 
-
==About this Structure==
+
==Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)==
-
[[3ir3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IR3 OCA].
+
<StructureSection load='3ir3' size='340' side='right'caption='[[3ir3]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[3ir3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IR3 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ir3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ir3 OCA], [https://pdbe.org/3ir3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ir3 RCSB], [https://www.ebi.ac.uk/pdbsum/3ir3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ir3 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/HTD2_HUMAN HTD2_HUMAN] Mitochondrial 3-hydroxyacyl-thioester dehydratase, which may be involved in fatty acid biosynthesis.<ref>PMID:17898086</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ir/3ir3_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ir3 ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Bountra, C.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Burgess-Brown, N.]]
+
[[Category: Bountra C]]
-
[[Category: Chaikuad, A.]]
+
[[Category: Burgess-Brown N]]
-
[[Category: Cocking, R.]]
+
[[Category: Chaikuad A]]
-
[[Category: Delft, F von.]]
+
[[Category: Cocking R]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Gileadi, O.]]
+
[[Category: Gileadi O]]
-
[[Category: Kavanagh, K L.]]
+
[[Category: Kavanagh KL]]
-
[[Category: Krojer, T.]]
+
[[Category: Krojer T]]
-
[[Category: Muniz, J.]]
+
[[Category: Muniz J]]
-
[[Category: Oppermann, U.]]
+
[[Category: Oppermann U]]
-
[[Category: Pilka, E.]]
+
[[Category: Pilka E]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Ugochukwu E]]
-
[[Category: Ugochukwu, E.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigelt, J.]]
+
[[Category: Von Delft F]]
-
[[Category: 3-hydroxyacyl-thioester dehydratase 2]]
+
-
[[Category: Htd2]]
+
-
[[Category: Lyase]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+

Current revision

Crystal structure of human 3-hydroxyacyl-thioester dehydratase 2 (HTD2)

PDB ID 3ir3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools