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3l5y

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Current revision (08:37, 19 March 2014) (edit) (undo)
(Redirecting to 4ps4)
 
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{{STRUCTURE_3l5y| PDB=3l5y | SCENE= }}
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#REDIRECT [[4ps4]] This PDB entry is obsolete and replaced by 4ps4
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===Crystal structure of the complex between IL-13 and M1295 FAB===
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{{ABSTRACT_PUBMED_20226193}}
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==Disease==
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[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:[http://omim.org/entry/607154 607154]]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
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==Function==
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[[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
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==About this Structure==
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[[3l5y]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L5Y OCA].
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==See Also==
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*[[Interleukin|Interleukin]]
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==Reference==
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<ref group="xtra">PMID:020226193</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Gilliland, G L.]]
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[[Category: Malia, T.]]
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[[Category: Obmolova, G.]]
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[[Category: Teplyakov, A.]]
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[[Category: Alpha-helical bundle]]
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[[Category: Cytokine]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Immune system]]
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[[Category: Immunoglobulin fold]]
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[[Category: Monoclonal antibody]]
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[[Category: Secreted]]
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Current revision

  1. REDIRECT 4ps4 This PDB entry is obsolete and replaced by 4ps4

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