1xni

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:51, 14 February 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_1xni| PDB=1xni | SCENE= }}
 
-
===Tandem Tudor Domain of 53BP1===
 
-
{{ABSTRACT_PUBMED_15525939}}
 
-
==Disease==
+
==Tandem Tudor Domain of 53BP1==
-
[[http://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN]] Note=A chromosomal aberration involving TP53BP1 is found in a form of myeloproliferative disorder chronic with eosinophilia. Translocation t(5;15)(q33;q22) with PDGFRB creating a TP53BP1-PDGFRB fusion protein.
+
<StructureSection load='1xni' size='340' side='right'caption='[[1xni]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[1xni]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XNI FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN]] Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.<ref>PMID:12364621</ref><ref>PMID:17190600</ref>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xni OCA], [https://pdbe.org/1xni PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xni RCSB], [https://www.ebi.ac.uk/pdbsum/1xni PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xni ProSAT]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[1xni]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XNI OCA].
+
== Disease ==
-
 
+
[https://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN] Note=A chromosomal aberration involving TP53BP1 is found in a form of myeloproliferative disorder chronic with eosinophilia. Translocation t(5;15)(q33;q22) with PDGFRB creating a TP53BP1-PDGFRB fusion protein.
-
==Reference==
+
== Function ==
-
<references group="xtra"/><references/>
+
[https://www.uniprot.org/uniprot/TP53B_HUMAN TP53B_HUMAN] Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.<ref>PMID:12364621</ref> <ref>PMID:17190600</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: DiTullio, R A.]]
+
[[Category: Large Structures]]
-
[[Category: Gorgoulis, V G.]]
+
[[Category: DiTullio Jr RA]]
-
[[Category: Halazonetis, T D.]]
+
[[Category: Gorgoulis VG]]
-
[[Category: Huyen, Y.]]
+
[[Category: Halazonetis TD]]
-
[[Category: Mellert, H S.]]
+
[[Category: Huyen Y]]
-
[[Category: Petty, T J.]]
+
[[Category: Mellert HS]]
-
[[Category: Sheston, E A.]]
+
[[Category: Petty TJ]]
-
[[Category: Stavridi, E S.]]
+
[[Category: Sheston EA]]
-
[[Category: Zacharatos, P.]]
+
[[Category: Stavridi ES]]
-
[[Category: Zgheib, O.]]
+
[[Category: Zacharatos P]]
-
[[Category: Bent beta-sheet]]
+
[[Category: Zgheib O]]
-
[[Category: Beta-barrel]]
+
-
[[Category: Cell cycle]]
+

Current revision

Tandem Tudor Domain of 53BP1

PDB ID 1xni

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xni"
Personal tools