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2cff

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[[Image:2cff.jpg|left|200px]]<br /><applet load="2cff" size="350" color="white" frame="true" align="right" spinBox="true"
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==CRYSTAL STRUCTURE OF N-((5'-PHOSPHORIBOSYL)-FORMIMINO)-5-AMINOIMIDAZOL-4-CARBOXAMID RIBONUCLEOTID ISOMERASE MUTANT D127V (EC 3.1.3.15, HISA)==
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caption="2cff, resolution 2.500&Aring;" />
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<StructureSection load='2cff' size='340' side='right' caption='[[2cff]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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'''CRYSTAL STRUCTURE OF N-((5'-PHOSPHORIBOSYL)-FORMIMINO)-5-AMINOIMIDAZOL-4-CARBOXAMID RIBONUCLEOTID ISOMERASE MUTANT D127V (EC 3.1.3.15, HISA)'''<br />
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2cff]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CFF FirstGlance]. <br>
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==About this Structure==
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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2CFF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] with <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/1-(5-phosphoribosyl)-5-_((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide_isomerase 1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.16 5.3.1.16] Known structural/functional Site: <scene name='pdbsite=AC1:Mpd+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CFF OCA].
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qo2|1qo2]]</td></tr>
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[[Category: 1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase]]
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/1-(5-phosphoribosyl)-5-_((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide_isomerase 1-(5-phosphoribosyl)-5- ((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.16 5.3.1.16] </span></td></tr>
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[[Category: Single protein]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cff FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cff OCA], [http://pdbe.org/2cff PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cff RCSB], [http://www.ebi.ac.uk/pdbsum/2cff PDBsum]</span></td></tr>
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[[Category: Thermotoga maritima]]
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</table>
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[[Category: He, C.]]
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== Evolutionary Conservation ==
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[[Category: Kuper, J.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Sterner, R.]]
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Check<jmol>
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[[Category: Wilmmans, M.]]
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<jmolCheckbox>
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[[Category: MPD]]
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cf/2cff_consurf.spt"</scriptWhenChecked>
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[[Category: amino-acid biosynthesis]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: histidine biosynthesis]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: isomerase]]
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</jmolCheckbox>
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[[Category: thermophilic protein]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cff ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:48:04 2008''
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__TOC__
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</StructureSection>
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[[Category: Atcc 43589]]
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[[Category: He, C]]
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[[Category: Kuper, J]]
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[[Category: Sterner, R]]
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[[Category: Wilmmans, M]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Histidine biosynthesis]]
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[[Category: Isomerase]]
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[[Category: Thermophilic protein]]

Current revision

CRYSTAL STRUCTURE OF N-((5'-PHOSPHORIBOSYL)-FORMIMINO)-5-AMINOIMIDAZOL-4-CARBOXAMID RIBONUCLEOTID ISOMERASE MUTANT D127V (EC 3.1.3.15, HISA)

2cff, resolution 2.50Å

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