2din

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:39, 22 May 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_2din| PDB=2din | SCENE= }}
 
-
===Solution structure of the Myb_DNA-binding domain of human Cell division cycle 5-like protein===
 
-
==Disease==
+
==Solution structure of the Myb_DNA-binding domain of human Cell division cycle 5-like protein==
-
[[http://www.uniprot.org/uniprot/CDC5L_HUMAN CDC5L_HUMAN]] Note=A chromosomal aberration involving CDC5L is found in multicystic renal dysplasia. Translocation t(6;19)(p21;q13.1) with USF2.
+
<StructureSection load='2din' size='340' side='right'caption='[[2din]]' scene=''>
-
 
+
== Structural highlights ==
-
==Function==
+
<table><tr><td colspan='2'>[[2din]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DIN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DIN FirstGlance]. <br>
-
[[http://www.uniprot.org/uniprot/CDC5L_HUMAN CDC5L_HUMAN]] DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.<ref>PMID:9038199</ref><ref>PMID:9632794</ref><ref>PMID:9468527</ref><ref>PMID:10570151</ref><ref>PMID:11101529</ref><ref>PMID:11082045</ref><ref>PMID:11544257</ref><ref>PMID:12927788</ref><ref>PMID:18583928</ref>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2din FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2din OCA], [https://pdbe.org/2din PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2din RCSB], [https://www.ebi.ac.uk/pdbsum/2din PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2din ProSAT], [https://www.topsan.org/Proteins/RSGI/2din TOPSAN]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[2din]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DIN OCA].
+
== Disease ==
-
 
+
[https://www.uniprot.org/uniprot/CDC5L_HUMAN CDC5L_HUMAN] Note=A chromosomal aberration involving CDC5L is found in multicystic renal dysplasia. Translocation t(6;19)(p21;q13.1) with USF2.
-
==Reference==
+
== Function ==
-
<references group="xtra"/><references/>
+
[https://www.uniprot.org/uniprot/CDC5L_HUMAN CDC5L_HUMAN] DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.<ref>PMID:9038199</ref> <ref>PMID:9632794</ref> <ref>PMID:9468527</ref> <ref>PMID:10570151</ref> <ref>PMID:11101529</ref> <ref>PMID:11082045</ref> <ref>PMID:11544257</ref> <ref>PMID:12927788</ref> <ref>PMID:18583928</ref>
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/di/2din_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2din ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Inoue, M.]]
+
[[Category: Large Structures]]
-
[[Category: Kigawa, T.]]
+
[[Category: Inoue M]]
-
[[Category: Koshiba, S.]]
+
[[Category: Kigawa T]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Koshiba S]]
-
[[Category: Tochio, N.]]
+
[[Category: Tochio N]]
-
[[Category: Yokoyama, S.]]
+
[[Category: Yokoyama S]]
-
[[Category: Yoneyama, M.]]
+
[[Category: Yoneyama M]]
-
[[Category: Cell cycle]]
+
-
[[Category: Dna binding]]
+
-
[[Category: Dna binding protein]]
+
-
[[Category: Myb_dna-binding domain]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Riken structural genomics/proteomics initiative]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Spliceosome]]
+
-
[[Category: Structural genomic]]
+

Current revision

Solution structure of the Myb_DNA-binding domain of human Cell division cycle 5-like protein

PDB ID 2din

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2din"
Personal tools