2cov
From Proteopedia
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| - | [[Image:2cov.gif|left|200px]]<br /><applet load="2cov" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2cov, resolution 1.25Å" /> | ||
| - | '''Crystal structure of CBM31 from beta-1,3-xylanase'''<br /> | ||
| - | == | + | ==Crystal structure of CBM31 from beta-1,3-xylanase== |
| + | <StructureSection load='2cov' size='340' side='right'caption='[[2cov]], [[Resolution|resolution]] 1.25Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2cov]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenes_sp._XY-234 Alcaligenes sp. XY-234]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2COV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cov FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cov OCA], [https://pdbe.org/2cov PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cov RCSB], [https://www.ebi.ac.uk/pdbsum/2cov PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cov ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
Here, we present the crystal structure of the family 31 carbohydrate-binding module (CBM) of beta-1,3-xylanase from Alcaligenes sp. strain XY-234 (AlcCBM31) determined at a resolution of 1.25A. The AlcCBM31 shows affinity with only beta-1,3-xylan. The AlcCBM31 molecule makes a beta-sandwich structure composed of eight beta-strands with a typical immunoglobulin fold and contains two intra-molecular disulfide bonds. The folding topology of AlcCBM31 differs from that of the large majority of other CBMs, in which eight beta-strands comprise a beta-sandwich structure with a typical jelly-roll fold. AlcCBM31 shows structural similarity with CBM structures of family 34 and family 9, which also adopt structures based on immunoglobulin folds. | Here, we present the crystal structure of the family 31 carbohydrate-binding module (CBM) of beta-1,3-xylanase from Alcaligenes sp. strain XY-234 (AlcCBM31) determined at a resolution of 1.25A. The AlcCBM31 shows affinity with only beta-1,3-xylan. The AlcCBM31 molecule makes a beta-sandwich structure composed of eight beta-strands with a typical immunoglobulin fold and contains two intra-molecular disulfide bonds. The folding topology of AlcCBM31 differs from that of the large majority of other CBMs, in which eight beta-strands comprise a beta-sandwich structure with a typical jelly-roll fold. AlcCBM31 shows structural similarity with CBM structures of family 34 and family 9, which also adopt structures based on immunoglobulin folds. | ||
| - | + | The first crystal structure of a family 31 carbohydrate-binding module with affinity to beta-1,3-xylan.,Hashimoto H, Tamai Y, Okazaki F, Tamaru Y, Shimizu T, Araki T, Sato M FEBS Lett. 2005 Aug 15;579(20):4324-8. PMID:16061225<ref>PMID:16061225</ref> | |
| - | + | ||
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | [[Category: Alcaligenes sp.]] | + | <div class="pdbe-citations 2cov" style="background-color:#fffaf0;"></div> |
| - | [[Category: | + | == References == |
| - | [[Category: Araki | + | <references/> |
| - | [[Category: Hashimoto | + | __TOC__ |
| - | [[Category: Okazaki | + | </StructureSection> |
| - | [[Category: Sato | + | [[Category: Alcaligenes sp. XY-234]] |
| - | [[Category: Shimizu | + | [[Category: Large Structures]] |
| - | [[Category: Tamai | + | [[Category: Araki T]] |
| - | [[Category: Tamaru | + | [[Category: Hashimoto H]] |
| - | + | [[Category: Okazaki F]] | |
| - | + | [[Category: Sato M]] | |
| - | + | [[Category: Shimizu T]] | |
| - | + | [[Category: Tamai Y]] | |
| - | + | [[Category: Tamaru Y]] | |
| - | + | ||
Current revision
Crystal structure of CBM31 from beta-1,3-xylanase
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