2cq0

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:28, 22 May 2024) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2cq0.gif|left|200px]]<br /><applet load="2cq0" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2cq0" />
 
-
'''solution structure of RNA binding domain in eukaryotic translation initiation factor 3 subunit 4'''<br />
 
-
==About this Structure==
+
==solution structure of RNA binding domain in eukaryotic translation initiation factor 3 subunit 4==
-
2CQ0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQ0 OCA].
+
<StructureSection load='2cq0' size='340' side='right'caption='[[2cq0]]' scene=''>
-
[[Category: Homo sapiens]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2cq0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CQ0 FirstGlance]. <br>
-
[[Category: Inoue, M.]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
[[Category: Kigawa, T.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cq0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cq0 OCA], [https://pdbe.org/2cq0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cq0 RCSB], [https://www.ebi.ac.uk/pdbsum/2cq0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cq0 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cq0 TOPSAN]</span></td></tr>
-
[[Category: Muto, Y.]]
+
</table>
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
== Function ==
-
[[Category: Shirouzu, M.]]
+
[https://www.uniprot.org/uniprot/EIF3G_HUMAN EIF3G_HUMAN] Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
-
[[Category: Terada, T.]]
+
== Evolutionary Conservation ==
-
[[Category: Tsuda, K.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Yokoyama, S.]]
+
Check<jmol>
-
[[Category: national project on protein structural and functional analyses]]
+
<jmolCheckbox>
-
[[Category: nppsfa]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cq/2cq0_consurf.spt"</scriptWhenChecked>
-
[[Category: riken structural genomics/proteomics initiative]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: rrm domain]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: rsgi]]
+
</jmolCheckbox>
-
[[Category: structural genomics]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cq0 ConSurf].
 +
<div style="clear:both"></div>
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:51:17 2008''
+
==See Also==
 +
*[[Eukaryotic initiation factor 3D structures|Eukaryotic initiation factor 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Inoue M]]
 +
[[Category: Kigawa T]]
 +
[[Category: Muto Y]]
 +
[[Category: Shirouzu M]]
 +
[[Category: Terada T]]
 +
[[Category: Tsuda K]]
 +
[[Category: Yokoyama S]]

Current revision

solution structure of RNA binding domain in eukaryotic translation initiation factor 3 subunit 4

PDB ID 2cq0

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2cq0"
Personal tools