2lx7

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{{STRUCTURE_2lx7| PDB=2lx7 | SCENE= }}
 
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===Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A===
 
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==Disease==
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==Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A==
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[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.
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<StructureSection load='2lx7' size='340' side='right'caption='[[2lx7]]' scene=''>
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== Structural highlights ==
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==Function==
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<table><tr><td colspan='2'>[[2lx7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LX7 FirstGlance]. <br>
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[[http://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN]] May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lx7 OCA], [https://pdbe.org/2lx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lx7 RCSB], [https://www.ebi.ac.uk/pdbsum/2lx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lx7 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[2lx7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LX7 OCA].
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== Disease ==
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[https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.
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== Function ==
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[https://www.uniprot.org/uniprot/GAS7_HUMAN GAS7_HUMAN] May play a role in promoting maturation and morphological differentiation of cerebellar neurons.
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Acton, T.]]
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[[Category: Large Structures]]
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[[Category: Dan, L.]]
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[[Category: Acton T]]
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[[Category: Everett, J K.]]
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[[Category: Dan L]]
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[[Category: Janjua, H.]]
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[[Category: Everett JK]]
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[[Category: Kennedy, M A.]]
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[[Category: Janjua H]]
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[[Category: Kohan, E.]]
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[[Category: Kennedy MA]]
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[[Category: Montelione, G T.]]
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[[Category: Kohan E]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Ramelot, T A.]]
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[[Category: Ramelot TA]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: Yang, Y.]]
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[[Category: Yang Y]]
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[[Category: Protein binding]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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[[Category: Target hr8574a]]
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Current revision

Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A

PDB ID 2lx7

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