2cz9

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[[Image:2cz9.gif|left|200px]]<br /><applet load="2cz9" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2cz9, resolution 1.50&Aring;" />
 
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'''Crystal Structure of galactokinase from Pyrococcus horikoshi'''<br />
 
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==About this Structure==
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==Crystal Structure of galactokinase from Pyrococcus horikoshi==
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2CZ9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Galactokinase Galactokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.6 2.7.1.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ9 OCA].
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<StructureSection load='2cz9' size='340' side='right'caption='[[2cz9]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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[[Category: Galactokinase]]
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2cz9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ9 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz9 OCA], [https://pdbe.org/2cz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz9 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz9 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz9 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GAL1_PYRHO GAL1_PYRHO] Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).<ref>PMID:16511293</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2cz9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cz9 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Single protein]]
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[[Category: Inagaki E]]
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[[Category: Inagaki, E.]]
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[[Category: Sakamoto K]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Shinkai A]]
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[[Category: Sakamoto, K.]]
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[[Category: Yokoyama S]]
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[[Category: Shinkai, A.]]
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[[Category: Yokoyama, S.]]
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[[Category: CL]]
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[[Category: GOL]]
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[[Category: galactokinase]]
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[[Category: national project on protein structural and functional analyses]]
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[[Category: nppsfa]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomics]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:53:51 2008''
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Current revision

Crystal Structure of galactokinase from Pyrococcus horikoshi

PDB ID 2cz9

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