2d3p
From Proteopedia
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| - | [[Image:2d3p.gif|left|200px]]<br /><applet load="2d3p" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2d3p, resolution 2.80Å" /> | ||
| - | '''Cratylia Floribunda seed lectin crystallized at basic pH'''<br /> | ||
| - | == | + | ==Cratylia Floribunda seed lectin crystallized at basic pH== |
| - | + | <StructureSection load='2d3p' size='340' side='right'caption='[[2d3p]], [[Resolution|resolution]] 2.80Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2d3p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Cratylia_argentea Cratylia argentea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D3P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D3P FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d3p OCA], [https://pdbe.org/2d3p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d3p RCSB], [https://www.ebi.ac.uk/pdbsum/2d3p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d3p ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LECA_CRAAG LECA_CRAAG] D-mannose/D-glucose-binding lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from rat. Induces lymphocyte proliferation and IFNG production.<ref>PMID:10747944</ref> <ref>PMID:1398779</ref> <ref>PMID:18472821</ref> <ref>PMID:7524287</ref> <ref>PMID:9575151</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d3/2d3p_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d3p ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Cratylia argentea]] | [[Category: Cratylia argentea]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Calvete | + | [[Category: Calvete JJ]] |
| - | [[Category: Cavada | + | [[Category: Cavada BS]] |
| - | [[Category: Sol | + | [[Category: Del Sol FG]] |
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Current revision
Cratylia Floribunda seed lectin crystallized at basic pH
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