2lu7

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{{STRUCTURE_2lu7| PDB=2lu7 | SCENE= }}
 
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===Solution NMR Structure of Ig like domain (1277-1357) of Obscurin-like protein 1 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8578D===
 
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==Disease==
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==Solution NMR Structure of Ig like domain (1277-1357) of Obscurin-like protein 1 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8578D==
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[[http://www.uniprot.org/uniprot/OBSL1_HUMAN OBSL1_HUMAN]] Defects in OBSL1 are the cause of 3M syndrome type 2 (3M2) [MIM:[http://omim.org/entry/612921 612921]]. An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, and normal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebral bodies.<ref>PMID:19481195</ref>
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<StructureSection load='2lu7' size='340' side='right'caption='[[2lu7]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2lu7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LU7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LU7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lu7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lu7 OCA], [https://pdbe.org/2lu7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lu7 RCSB], [https://www.ebi.ac.uk/pdbsum/2lu7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lu7 ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/OBSL1_HUMAN OBSL1_HUMAN] Defects in OBSL1 are the cause of 3M syndrome type 2 (3M2) [MIM:[https://omim.org/entry/612921 612921]. An autosomal recessive disorder characterized by severe pre- and postnatal growth retardation, facial dysmorphism, large head circumference, and normal intelligence and endocrine function. Skeletal changes include long slender tubular bones and tall vertebral bodies.<ref>PMID:19481195</ref>
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== Function ==
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[https://www.uniprot.org/uniprot/OBSL1_HUMAN OBSL1_HUMAN]
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==About this Structure==
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==See Also==
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[[2lu7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LU7 OCA].
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*[[Obscurin|Obscurin]]
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== References ==
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==Reference==
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<references/>
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<references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Acton, T B.]]
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[[Category: Large Structures]]
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[[Category: Eletsky, A.]]
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[[Category: Acton TB]]
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[[Category: Everett, J K.]]
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[[Category: Eletsky A]]
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[[Category: Janjua, H.]]
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[[Category: Everett JK]]
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[[Category: Kohan, E.]]
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[[Category: Janjua H]]
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[[Category: Lee, D.]]
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[[Category: Kohan E]]
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[[Category: Montelione, G T.]]
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[[Category: Lee D]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Pulavarti, S.]]
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[[Category: Pulavarti S]]
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[[Category: Satyamoorthy, B.]]
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[[Category: Satyamoorthy B]]
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[[Category: Sukumaran, D K.]]
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[[Category: Sukumaran DK]]
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[[Category: Szyperski, T.]]
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[[Category: Szyperski T]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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[[Category: Structural protein]]
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Current revision

Solution NMR Structure of Ig like domain (1277-1357) of Obscurin-like protein 1 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8578D

PDB ID 2lu7

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