2dbh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (16:34, 13 December 2023) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2dbh.jpg|left|200px]]<br /><applet load="2dbh" size="350" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2dbh" />
 
-
'''Solution structure of the carboxyl-terminal CARD-like domain in human TNFR-related death receptor-6'''<br />
 
-
==About this Structure==
+
==Solution structure of the carboxyl-terminal CARD-like domain in human TNFR-related death receptor-6==
-
2DBH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DBH OCA].
+
<StructureSection load='2dbh' size='340' side='right'caption='[[2dbh]]' scene=''>
-
[[Category: Homo sapiens]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2dbh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DBH FirstGlance]. <br>
-
[[Category: Inoue, M.]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
[[Category: Kigawa, T.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dbh OCA], [https://pdbe.org/2dbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dbh RCSB], [https://www.ebi.ac.uk/pdbsum/2dbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dbh ProSAT], [https://www.topsan.org/Proteins/RSGI/2dbh TOPSAN]</span></td></tr>
-
[[Category: Koshiba, S.]]
+
</table>
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
== Function ==
-
[[Category: Saito, K.]]
+
[https://www.uniprot.org/uniprot/TNR21_HUMAN TNR21_HUMAN] May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
-
[[Category: Yokoyama, S.]]
+
-
[[Category: apoptosis]]
+
-
[[Category: national project on protein structural and functional analyses]]
+
-
[[Category: nf-kappab]]
+
-
[[Category: nppsfa]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: structural genomics]]
+
-
[[Category: tnf receptor superfamily]]
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:57:06 2008''
+
==See Also==
 +
*[[Tumor necrosis factor receptor 3D structures|Tumor necrosis factor receptor 3D structures]]
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Inoue M]]
 +
[[Category: Kigawa T]]
 +
[[Category: Koshiba S]]
 +
[[Category: Saito K]]
 +
[[Category: Yokoyama S]]

Current revision

Solution structure of the carboxyl-terminal CARD-like domain in human TNFR-related death receptor-6

PDB ID 2dbh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2dbh"
Personal tools