4ijj
From Proteopedia
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| - | {{STRUCTURE_4ijj| PDB=4ijj | SCENE= }} | ||
| - | ===Structure of transcription factor DksA2 from Pseudomonas aeruginosa=== | ||
| - | {{ABSTRACT_PUBMED_23416301}} | ||
| - | == | + | ==Structure of transcription factor DksA2 from Pseudomonas aeruginosa== |
| - | [[4ijj]] is a 3 chain structure with sequence from [ | + | <StructureSection load='4ijj' size='340' side='right'caption='[[4ijj]], [[Resolution|resolution]] 3.25Å' scene=''> |
| - | [[ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[4ijj]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_UCBPP-PA14 Pseudomonas aeruginosa UCBPP-PA14]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IJJ FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ijj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ijj OCA], [https://pdbe.org/4ijj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ijj RCSB], [https://www.ebi.ac.uk/pdbsum/4ijj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ijj ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | <div style="background-color:#fffaf0;"> |
| - | [[Category: | + | == Publication Abstract from PubMed == |
| - | [[Category: | + | Transcription factor DksA contains a four-Cys Zn(2 +)-finger motif thought to be responsible for structural integrity and the relative disposition of its domains. Pseudomonas aeruginosa encodes an additional DksA paralog (DksA2) that is expressed selectively under Zn(2+) limitation. Although DksA2 does not bind Zn(2+), it complements the Escherichia coli dksA deletion and has similar effects on transcription in vitro. In this study, structural and biochemical analyses reveal that DksA2 has a similar fold, domain structure and RNA polymerase binding properties to those of the E. coli DksA despite the lack of the stabilizing metal ion. Structured summary of protein interactions: RNAPandDksA2bindbybiochemical(View interaction) DksAandRNAPbindbybiochemical(View interaction) DksA2andDksA2bindbyX-ray crystallography(View interaction). |
| - | [[Category: | + | |
| + | DksA2, a zinc-independent structural analog of the transcription factor DksA.,Furman R, Biswas T, Danhart EM, Foster MP, Tsodikov OV, Artsimovitch I FEBS Lett. 2013 Feb 14. pii: S0014-5793(13)00123-3. doi:, 10.1016/j.febslet.2013.01.073. PMID:23416301<ref>PMID:23416301</ref> | ||
| + | |||
| + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| + | </div> | ||
| + | <div class="pdbe-citations 4ijj" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas aeruginosa UCBPP-PA14]] | ||
| + | [[Category: Artsimovitch I]] | ||
| + | [[Category: Biswas T]] | ||
| + | [[Category: Furman R]] | ||
| + | [[Category: Tsodikov OV]] | ||
Current revision
Structure of transcription factor DksA2 from Pseudomonas aeruginosa
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