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3qxx

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{{STRUCTURE_3qxx| PDB=3qxx | SCENE= }}
 
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===Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GDP and 8-aminocaprylic acid===
 
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{{ABSTRACT_PUBMED_22284390}}
 
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==Function==
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==Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GDP and 8-aminocaprylic acid==
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[[http://www.uniprot.org/uniprot/BIOD_HELPY BIOD_HELPY]] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity).[HAMAP-Rule:MF_00336]
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<StructureSection load='3qxx' size='340' side='right'caption='[[3qxx]], [[Resolution|resolution]] 1.36&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3qxx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QXX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QXX FirstGlance]. <br>
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[[3qxx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QXX OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.36&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8AC:8-AMINOOCTANOIC+ACID'>8AC</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qxx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qxx OCA], [https://pdbe.org/3qxx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qxx RCSB], [https://www.ebi.ac.uk/pdbsum/3qxx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qxx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BIOD_HELPY BIOD_HELPY] Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity).[HAMAP-Rule:MF_00336]
==See Also==
==See Also==
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*[[Dethiobiotin synthetase|Dethiobiotin synthetase]]
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*[[Dethiobiotin synthetase 3D structures|Dethiobiotin synthetase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:022284390</ref><references group="xtra"/><references/>
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[[Category: Dethiobiotin synthase]]
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[[Category: Helicobacter pylori 26695]]
[[Category: Helicobacter pylori 26695]]
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[[Category: Chruszcz, M.]]
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[[Category: Large Structures]]
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[[Category: Joachimiak, A.]]
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[[Category: Chruszcz M]]
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[[Category: Klimecka, M M.]]
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[[Category: Joachimiak A]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Klimecka MM]]
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[[Category: Minor, W.]]
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[[Category: Minor W]]
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[[Category: Murzyn, K.]]
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[[Category: Murzyn K]]
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[[Category: Porebski, P J.]]
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[[Category: Porebski PJ]]
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[[Category: Dethiobiotin synthetase]]
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[[Category: Dtb]]
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[[Category: Ligase]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-biology]]
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[[Category: Structural genomic]]
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Current revision

Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with GDP and 8-aminocaprylic acid

PDB ID 3qxx

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